Faculty Research 1980 - 1989

Title

A fragment of the simian virus 40 early genome can induce tumors in nude mice.

Document Type

Article

Publication Date

1985

Keywords

Cell-Transformation-Neoplastic, Genes-Viral, Mice, Mice-Inbred-BALB-C, Mice-Nude, SUPPORT-U-S-GOVT-P-H-S, SV40-Virus: ge

JAX Source

J Virol 1985 Mar;53(3):988-9

Grant

CA37303, CA21124, CA34072

Abstract

Cell lines transformed by simian virus 40 mutant F8dl (deleted from 0.168 to 0.424 map units, corresponding to the carboxy-terminal 62% of the wild-type simian virus 40 large tumor antigen) are tumorigenic in nude mice. Four of five C3H10T1/2 cell lines transformed by F8dl were tumorigenic in nude mice, whereas two of two wild-type transformants were tumorigenic.

Please contact the Joan Staats Library for information regarding this document.

Share

COinS