Faculty Research 1980 - 1989
Title
Characterization of somatically acquired ecotropic and mink cell focus-forming viruses in lymphomas of AKXD recombinant inbred mice.
Document Type
Article
Publication Date
1987
Keywords
Animal, Chromosome-Mapping, DNA-Viral, Lymphoma, Mice-Inbred-DBA, Mink-Cell-Focus-Inducing-Viruses Mouse-Leukemia-Viruses, Proto-Oncogenes, Recombination-Genetic
First Page
2929
Last Page
2933
JAX Source
J Virol. 1987 Sep; 61(9):2929-33.
Grant
CA37283, CA33093, N01-CO-23909
Abstract
The DNA of lymphomas from 12 AKXD recombinant inbred mouse strains was analyzed to determine the presence of somatically acquired ecotropic and mink cell focus-forming proviruses. Mink cell focus-forming proviruses were associated primarily with T-cell lymphomas, whereas ecotropic proviruses were associated with lymphomas of B-cell and myeloid lineages. A model based on the results is proposed to explain the variation in lymphoma types observed in different AKXD strains.
Recommended Citation
Mucenski, M L.; Taylor, B A.; Copeland, N G.; and Jenkins, N A., " Characterization of somatically acquired ecotropic and mink cell focus-forming viruses in lymphomas of AKXD recombinant inbred mice." (1987). Faculty Research 1980 - 1989. 859.
https://mouseion.jax.org/stfb1980_1989/859