Faculty Research 1980 - 1989

Title

Localization of the inosine triphosphatase locus (Itp) on chromosome 2 of the mouse.

Document Type

Article

Publication Date

1987

Keywords

Chromosome-Mapping, Linkage-(Genetics), Mice, Mice-Inbred-Strains: ge, Pyrophosphatases: ge, Species-Specificity, SUPPORT-U-S-GOVT-P-H-S, Variation-(Genetics)

JAX Source

Biochem-Genet. 1987 Apr; 25(3-4):267-74.

Grant

GM18684, CA33093

Abstract

An electrophoretic variant of the enzyme inosine triphosphatase was found by screening inbred strains of mice. Strains with the slower-migrating variant include BALB/cJ, DBA/1J, and PL/J. The Itp locus was mapped between the beta-2-microglobulin (B2m) and the agouti (a) loci on chromosome 2. The mapping of Itp on chromosome 2 identifies a chromosomal segment that has been conserved since the divergence of lineages leading to mouse and man.

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