Papillomavirus infection of aged Persian cats.
Cat-Diseases: mi, pa, Cats, DNA-Viral: an, Immunohistochemistry, Male, Microscopy-Electron, Nucleic-Acid-Hybridization, Papillomaviruses: ge, ul, SUPPORT-NON-U-S-GOVT, Tumor-Virus-Infections: mi, pa, ve, Virion: ul
J Vet Diagn Invest 1990 Oct; 2(4):294-9.
Papillomavirus infection was confirmed in 2 Persian cats with sessile hyperkeratotic skin lesions. Skin lesions were not typical papillomas as found in other species. Papillomavirus were demonstrated in negative stain preparations of homogenized tissue and within nuclei of cells in the stratum granulosum. Papillomavirus group-specific antigens were detected within nuclei corresponding to those containing virions. Attempts to transmit this disease to other cats or propagate the virus in tissue cultures were unsuccessful. A 7.8-kilobase DNA molecule was present in low-stringency Southern blots usng a bovine papillomavirus type 1 cloned DNA probe. In reverse Southern blots, the cat papillomavirus hybridized under conditions of low stringency with all papillomavirus genomes tested. Combined with limited restriction endonuclease restriction mapping, the above information indicates that the feline cutaneous papillomavirus is a unique virus type and thus expands the list of hosts known to be infected by papillomaviruses.
Carney, H C.; England, J J.; Hodgin, E C.; Whiteley, H E.; Adkison, D L.; and Sundberg, J P., " Papillomavirus infection of aged Persian cats." (1990). Faculty Research 1990 - 1999. 81.
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