Faculty Research 1990 - 1999

Mapping in the region of Danforth's short tail and the localization of tail length modifiers.

Document Type


Publication Date



Animal, Chromosome-Mapping, Chromosomes-Human-Pair-1: ge, Chromosomes-Human-Pair-10: ge, Chromosomes-Human-Pair-18: ge, Chromosomes-Human-Pair-9: ge, Female, Genetic-Markers, Genome, Haplotypes, Human, Linkage-(Genetics), Male, Mice, Mice-Inbred-CBA, Mice-Mutant-Strains: ge, Polymorphism-(Genetics), Repetitive-Sequences-Nucleic-Acid, Sequence-Analysis-DNA, SUPPORT-NON-U-S-GOVT, Tail: ab

First Page


Last Page


JAX Source

Genome Res 1997 Feb;7(2):108-17


We have used an interspecific backcross to generate a detailed genetic map around the mouse tail and kidney developmental mutation Danforth's short tail (Sd). The map includes 14 simple sequence repeat (SSR) markers and four genes in a 5-cM region encompassing Sd. In addition we have used a DNA pooling approach to carry out a genome scan to localize quantitative trait loci (QTL) that modify the tail length of Sd progeny of the backcross. This has allowed us to identify a major QTL on chromosome 10 in the region of nodal and three other putative tail length QTL on chromosomes 1, 9, and 18.

Please contact the Joan Staats Library for information regarding this document.