Isolation and cloning of a papillomavirus from a North American porcupine by using multiply primed rolling-circle amplification: the Erethizon dorsatum papillomavirus type 1.

Document Type


Publication Date



DNA-Circular, DNA-Viral, Dermatomycoses, Genome-Viral, North-America, Nucleic-Acid-Amplification-Techniques, Papillomavirus, Porcupines

JAX Source

Virology 2005 Jan; 331(2):449-56


The complete genome of a novel papillomavirus was isolated from a cutaneous papillomatous lesion of a North American porcupine (Erethizon dorsatum) using multiply primed rolling-circle amplification (RCA). The nucleotide sequence, genome organization, and phylogenetic position of the Erethizon dorsatum papillomavirus type 1 (EdPV-1) were determined. EdPV-1 is only distantly related to other benign cutaneous papillomavirus sequences and is the first member of the novel Sigma papillomavirus genus.