Title
Chromosomal inversion discovered in C3H/HeJ mice.
Document Type
Article
Publication Date
2006
First Page
311
Last Page
313
JAX Source
Genomics 2006 Feb; 87(2):311-3.
Abstract
Mice of the inbred mouse strain C3H/HeJ have been shown to be homozygous for a chromosomal inversion on Chromosome (Chr) 6. The inversion encompasses about 20% of the chromosome from approximately 73 Mb to approximately 116 Mb. The importance of this finding is that linkage crosses using C3H/HeJ will show no recombination in this region of Chr 6. The inversion has no apparent effect on the phenotype of C3H/HeJ mice and its presence should not affect biological studies; however, use of C3H/HeJ mice for genetic analysis of Chr 6 should be avoided or the results interpreted with the inversion in mind. The inversion has been named In(6)1J (inversion Chr 6, Jackson 1).
Recommended Citation
Akeson EC,
Donahue LR,
Beamer WG,
Shultz KL,
Ackert BC,
Rosen CJ,
Corrigan J,
Davisson MT.
Chromosomal inversion discovered in C3H/HeJ mice. Genomics 2006 Feb; 87(2):311-3.