A revised nomenclature for the human and rodent alpha-tubulin gene family.
Document Type
Article
Publication Date
2007
Keywords
DNA-Complementary, Humans, Mice, Multigene-Family, Phylogeny, Rats, Terminology-as-Topic, Tubulin
First Page
285
Last Page
289
JAX Source
Genomics 2007 Aug; 90(2):285-9.
Abstract
An essential component of microtubules, alpha-tubulin is also a multigene family in many species. An orthology-based nomenclature for this gene family has previously been difficult to assign due to incomplete genome builds and the high degree of sequence similarity between members of this family. Using the current genome builds, sequence analysis of human, mouse, and rat alpha-tubulin genes has enabled an updated nomenclature to be generated. This revised nomenclature provides a unified language for the discussion of these genes in mammalian species; it has been approved by the gene nomenclature committees of the three species and is supported by researchers in the field.
Recommended Citation
Khodiyar VK,
Maltais LJ,
Sneddon KM,
Smith JR,
Shimoyama M,
Cabral F,
Dumontet C,
Dutcher SK,
Harvey RJ,
Lafanechere L,
Murray JM,
Nogales E,
Piquemal D,
Stanchi F,
Povey S,
Lovering RC.
A revised nomenclature for the human and rodent alpha-tubulin gene family. Genomics 2007 Aug; 90(2):285-9.