International Workshop on Lessons from Animal Models for Human Type 1 Diabetes: analyzing target autoantigens of humoral immunity in nonobese diabetic mice.
Autoantibodies, Autoantigens, Diabetes-Mellitus-Insulin-Dependent, Disease-Models-Animal, Glutamate-Decarboxylase, Human, Insulin, Mice, Mice-Inbred-NOD
see Reprint Collection
Ann N Y Acad Sci 2002 Apr; 958:1-2.
The aim of this workshop was to identify autoantibody assays that could provide useful markers of autoimmunity in the NOD mouse model for type 1 diabetes. It was demonstrated that insulin autoantibodies measured by sensitive radiobinding assay are a marker of autoimmunity in NOD mice and draw into question the true nature of GADA and IA-2A in this animal model.
Bonifacio, E; Atkinson, M; Eisenbarth, G; Serreze, D; Kay, T W.; Lee, Chan E.; and Singh, B, " International Workshop on Lessons from Animal Models for Human Type 1 Diabetes: analyzing target autoantigens of humoral immunity in nonobese diabetic mice." (2002). Faculty Research 2000 - 2009. 389.