Cutaneous fibropapilloma in a mountain lion (Felis concolor).

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Base-Sequence, Carnivora, Diagnosis-Differential, Female, Fibroma, Molecular-Sequence-Data, Neoplasm-Recurrence-Local, Papilloma, Papillomavirus, Papillomavirus-Infections, Polymerase-Chain-Reaction, Sequence-Alignment, Skin-Neoplasms

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see Reprint Collection

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J Zoo Wildl Med 2003 Jun; 34(2):179-83.


A 12-yr-old mountain lion (Felis concolor) developed a 0.5-cm3 raised nonpigmented and nonulcerated mass between the lip and the nasal planum. The tumor was surgically removed and diagnosed histologically as a fibropapilloma. The tumor recurred 1 yr later, at which time it was again excised, and the diagnosis was reconfirmed by biopsy. Frozen tissue from the second excision was submitted for polymerase chain reaction testing for papillomavirus. The 176-base pair polymerase chain reaction product recovered from the tumor was cloned and sequenced. The papillomavirus had 96% homology with a papillomavirus previously retrieved from a fibropapilloma in a domestic cat and is the next most closely related to bovine papillomavirus type 1. This is the first report of a virus-associated fibropapilloma in a mountain lion.

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