Mammalian septins nomenclature.
Document Type
Article
Publication Date
2002
Keywords
Animals, Fungal-Proteins, GTP-Phosphohydrolases, GTP-Binding-Proteins, Humans, Phylogeny, Protein-Structure-Tertiary, Terminology
First Page
4111
Last Page
4113
JAX Source
Mol Biol Cell 2002 Dec; 13(12):4111-3.
Abstract
There are 10 known mammalian septin genes, some of which produce multiple splice variants. The current nomenclature for the genes and gene products is very confusing, with several different names having been given to the same gene product and distinct names given to splice variants of the same gene. Moreover, some names are based on those of yeast or Drosophila septins that are not the closest homologues. Therefore, we suggest that the mammalian septin field adopt a common nomenclature system, based on that adopted by the Mouse Genomic Nomenclature Committee and accepted by the Human Genome Organization Gene Nomenclature Committee. The human and mouse septin genes will be named SEPT1-SEPT10 and Sept1-Sept10, respectively. Splice variants will be designated by an underscore followed by a lowercase "v" and a number, e.g., SEPT4_v1.
Recommended Citation
Macara IG,
Baldarelli R,
Field CM,
Glotzer M,
Low C,
Maltais LJ,
McKenzie L,
Robinson PJ,
Russell SE,
Trimble WS,
Ware J,
Zieger B.
Mammalian septins nomenclature. Mol Biol Cell 2002 Dec; 13(12):4111-3.