The subventricular zone: new molecular and cellular developments.
Document Type
Article
Publication Date
2002
Keywords
Carrier-Proteins, Cell-Differentiation, Cell-Movement, Cerebral-Cortex, Lateral-Ventricles, Membrane-Proteins, Neurons, Proteins, Receptors-Notch, Signal-Transduction, Stem-Cells
First Page
2128
Last Page
2135
JAX Source
Cell Mol Life Sci 2002 Dec; 59(12):2128-35.
Abstract
The subventricular zone (SVZ), which lines the lateral walls of the lateral ventricle, persists as a neurogenic zone into adulthood and functions as the largest site of neurogenesis in the adult brain. In recent years, with the acceptance of the concept of postembryonic mammalian neurogenesis, neurogenesis in the adult SVZ has been an area of active research. With the rapid accumulation of new information on the SVZ, some of which is contradictory, summarizing existing knowledge on the SVZ and outlining future research directions in this area become important. In this review, we will cover recent molecular and cellular investigations that characterize the SVZ niche, SVZ neurogenesis, and SVZ cell migration within the adult brain.
Recommended Citation
Conover JC,
Allen RL.
The subventricular zone: new molecular and cellular developments. Cell Mol Life Sci 2002 Dec; 59(12):2128-35.