Open chromatin profiling as a novel strategy for identifying cancer cell of origin.
Document Type
Article
Publication Date
9-30-2016
JAX Location
Reprint Collection
JAX Source
Mol Cell Oncol 2016 Sep 30; 3(6):e1236770
Volume
3
Issue
6
First Page
1236770
Last Page
1236770
PMID
28090579
Grant
CA184851, CA034196, HD007065
Abstract
Tumor cell of origin is an important prognostic measure but is challenging to assess. We recently demonstrated in acute myeloid leukemia (AML) that the chromatin landscape serves as a biomarker of transformed cell of origin. Thus, open chromatin loci offer important prognostic information as well as targets for development of novel therapies in cancer treatment. Mol Cell Oncol 2016 Sep 30; 3(6):e1236770
Recommended Citation
Young K,
Trowbridge JJ.
Open chromatin profiling as a novel strategy for identifying cancer cell of origin. Mol Cell Oncol 2016 Sep 30; 3(6):e1236770
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