A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects.
Adv Exp Med Biol 2016; 854:177-83.
Mouse models provide important resources for many areas of vision research, pertaining to retinal development, retinal function and retinal disease. The Translational Vision Research Models (TVRM) program uses chemical mutagenesis to generate new mouse models for vision research. In this chapter, we report the identification of mouse models for Grm1, Grk1 and Lrit3. Each of these is characterized by a primary defect in the electroretinogram. All are available without restriction to the research community. Adv Exp Med Biol 2016; 854:177-83.
Charette, Jeremy R.; Samuels, Ivy S; Yu, Minzhong; Stone, Lisa; Hicks, Wanda L.; Shi, Lan Ying; Krebs, Mark P.; Naggert, Juergen K.; Nishina, Patsy M.; and Peachey, Neal S, "A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects." (2016). Faculty Research 2016. 3.