Document Type

Article

Publication Date

1-1-2019

Keywords

JMG

JAX Source

Front Immunol 2019 Jan 31; 10:99

PMID

30766536

DOI

https://doi.org/10.3389/fimmu.2019.00099

Abstract

Type 1 diabetes (T1D) is a T cell mediated autoimmune disease that affects more than 19 million people with incidence increasing rapidly worldwide. For T cells to effectively drive T1D, they must first traffic to the islets and extravasate through the islet vasculature. Understanding the cues that lead to T cell entry into inflamed islets is important because diagnosed T1D patients already have established immune infiltration of their islets. Here we show that CD11c

Comments

Open access under Creative Commons Attribution (CC BY) license

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