Document Type
Article
Publication Date
1-1-2019
Keywords
JMG
JAX Source
Front Immunol 2019 Jan 31; 10:99
Volume
10
First Page
99
Last Page
99
ISSN
1664-3224
PMID
30766536
DOI
https://doi.org/10.3389/fimmu.2019.00099
Abstract
Type 1 diabetes (T1D) is a T cell mediated autoimmune disease that affects more than 19 million people with incidence increasing rapidly worldwide. For T cells to effectively drive T1D, they must first traffic to the islets and extravasate through the islet vasculature. Understanding the cues that lead to T cell entry into inflamed islets is important because diagnosed T1D patients already have established immune infiltration of their islets. Here we show that CD11c
Recommended Citation
Sandor A,
Lindsay R,
Dyjack N,
Whitesell J,
Rios C,
Bradley B,
Haskins K,
Serreze DV,
Geurts A,
Chen Y,
Seibold M,
Jacobelli J,
Friedman R.
CD11c+ Cells Are Gatekeepers for Lymphocyte Trafficking to Infiltrated Islets During Type 1 Diabetes. Front Immunol 2019 Jan 31; 10:99
Comments
Open access under Creative Commons Attribution (CC BY) license