The Salivary Mycobiome Contains 2 Ecologically Distinct Mycotypes.
JMG, Adult, Aged, Bacteria, Cross-Sectional Studies, Female, Fungi, Humans, Malassezia, Male, Middle Aged, Mycobiome
J Dent Res 2020 Jun; 99(6):730-738
A broad range of fungi has been detected in molecular surveys of the oral mycobiome. However, knowledge is still lacking on interindividual variability of these communities and the ecologic and clinical significance of oral fungal commensals. In this cross-sectional study, we use internal transcribed spacer 1 amplicon sequencing to evaluate the salivary mycobiome in 59 subjects, 36 of whom were scheduled to receive cancer chemotherapy. Analysis of the broad population structure of fungal communities in the whole cohort identified 2 well-demarcated genus-level community types (mycotypes), with
Hong, Bo-Young; Hoare, A; Cardenas, A; Dupuy, A K; Choquette, L; Salner, A L; Schauer, P K; Hegde, U; Peterson, D E; Dongari-Bagtzoglou, A; Strausbaugh, L D; and Diaz, P I, "The Salivary Mycobiome Contains 2 Ecologically Distinct Mycotypes." (2020). Faculty Research 2020. 291.