The Salivary Mycobiome Contains 2 Ecologically Distinct Mycotypes.
Document Type
Article
Publication Date
6-2020
Keywords
JMG, Adult, Aged, Bacteria, Cross-Sectional Studies, Female, Fungi, Humans, Malassezia, Male, Middle Aged, Mycobiome
JAX Source
J Dent Res 2020 Jun; 99(6):730-738
Volume
99
Issue
6
First Page
730
Last Page
738
ISSN
1544-0591
PMID
32315566
DOI
https://doi.org/10.1177/0022034520915879
Abstract
A broad range of fungi has been detected in molecular surveys of the oral mycobiome. However, knowledge is still lacking on interindividual variability of these communities and the ecologic and clinical significance of oral fungal commensals. In this cross-sectional study, we use internal transcribed spacer 1 amplicon sequencing to evaluate the salivary mycobiome in 59 subjects, 36 of whom were scheduled to receive cancer chemotherapy. Analysis of the broad population structure of fungal communities in the whole cohort identified 2 well-demarcated genus-level community types (mycotypes), with
Recommended Citation
Hong B,
Hoare A,
Cardenas A,
Dupuy A,
Choquette L,
Salner A,
Schauer P,
Hegde U,
Peterson D,
Dongari-Bagtzoglou A,
Strausbaugh L,
Diaz P.
The Salivary Mycobiome Contains 2 Ecologically Distinct Mycotypes. J Dent Res 2020 Jun; 99(6):730-738