Know Your Model: How essential is that essential gene?
Lab Anim (NY) 2020 Jan; 49(1):9-10
Many studies have reported on the identification of ‘essential genes’ in mice, but the context of the experimental model, including genetic background and specific molecular details of the allele, may impact the influence of alleles on viability.
Bello, Susan M.; Berry, Melissa L.; and Smith, Cynthia L, "Know Your Model: How essential is that essential gene?" (2020). Faculty Research 2020. 5.