Distinct Mechanisms of Dissemination of NDM-1 Metallo-β-Lactamase in
Document Type
Article
Publication Date
5-2020
Keywords
JGM
JAX Source
Antimicrob Agents Chemother 2020 May; 64(5):E00324-20
Volume
64
Issue
5
ISSN
1098-6596
PMID
32122888
DOI
https://doi.org/10.1128/AAC.00324-20
Abstract
A 4-year surveillance of carbapenem-resistant Acinetobacter spp. isolates in Argentina identified 40 strains carrying bla NDM-1 Genome sequencing revealed that most were Acinetobacter baumannii, whereas seven represented other Acinetobacter spp. The A. baumannii genomes were closely related, suggesting recent spread. bla NDM-1 was located in the chromosome of A. baumannii strains and on a plasmid in non-A. baumanniistrains. A resistance gene island carrying bla PER-7 and other resistance determinants was found on a plasmid in some A. baumannii strains.
Recommended Citation
Adams M,
Pasteran F,
Traglia G,
Martinez J,
Huang F,
Liu C,
Fernandez J,
Lopez C,
Gonzalez L,
Albornoz E,
Corso A,
Vila A,
Bonomo R,
Ramirez M.
Distinct Mechanisms of Dissemination of NDM-1 Metallo-β-Lactamase in Antimicrob Agents Chemother 2020 May; 64(5):E00324-20