Distinct Mechanisms of Dissemination of NDM-1 Metallo-β-Lactamase in
Antimicrob Agents Chemother 2020 May; 64(5):E00324-20
A 4-year surveillance of carbapenem-resistant Acinetobacter spp. isolates in Argentina identified 40 strains carrying bla NDM-1 Genome sequencing revealed that most were Acinetobacter baumannii, whereas seven represented other Acinetobacter spp. The A. baumannii genomes were closely related, suggesting recent spread. bla NDM-1 was located in the chromosome of A. baumannii strains and on a plasmid in non-A. baumanniistrains. A resistance gene island carrying bla PER-7 and other resistance determinants was found on a plasmid in some A. baumannii strains.
Adams, Mark D; Pasteran, Fernando; Traglia, German M; Martinez, Jasmine; Huang, Fanny; Liu, Christine; Fernandez, Jennifer S; Lopez, Carolina; Gonzalez, Lisandro J; Albornoz, Ezequiel; Corso, Alejandra; Vila, Alejandro J; Bonomo, Robert A; and Ramirez, Maria Soledad, "Distinct Mechanisms of Dissemination of NDM-1 Metallo-β-Lactamase in" (2020). Faculty Research 2020. 78.