Glucose metabolic profiles evaluated by PET associated with molecular characteristic landscape of gastric cancer.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
JGM, Fluorodeoxyglucose F18, Glucose, Glycine Plasma Membrane Transport Proteins, Humans, Metabolome, Positron-Emission Tomography, Radiopharmaceuticals, Stomach Neoplasms
Gastric Cancer 2022 Jan; 25(1):149-160
BACKGROUND: Although FDG-PET is widely used in cancer, its role in gastric cancer (GC) is still controversial due to variable [
METHODS: Based on a genetic signature, PETscore, representing [
RESULTS: Five genes, PLS1, PYY, HBQ1, SLC6A5, and NAT16, were identified for the predictive model for [
CONCLUSION: Our findings suggest that molecular characteristics are underlying the diverse metabolic profiles of GC. Diverse glucose metabolic profiles may apply to precise diagnostic and therapeutic approaches for GC.
Bae, Seong-Woo; Berlth, Felix; Jeong, Kyoung-Yun; Park, Ji-Hyeon; Choi, Jong-Ho; Park, Shin-Hoo; Suh, Yun-Suhk; Kong, Seong-Ho; Park, Do-Joong; Lee, Hyuk-Joon; Lee, Charles; Kim, Jong-Il; Youn, Hyewon; Choi, Hongyoon; Cheon, Gi Jeong; Kang, Keon Wook; and Yang, Han-Kwang, "Glucose metabolic profiles evaluated by PET associated with molecular characteristic landscape of gastric cancer." (2022). Faculty Research 2022. 25.