Document Type
Article
Publication Date
10-15-2024
Original Citation
Hutchinson A,
Appeltant R,
Burdon T,
Bao Q,
Bargaje R,
Bodnar A,
Chambers S,
Comizzoli P,
Cook L,
Endo Y,
Harman B,
Hayashi K,
Hildebrandt T,
Korody M,
Lakshmipathy U,
Loring J,
Munger C,
Ng A,
Novak B,
Onuma M,
Ord S,
Paris M,
Pask A,
Pelegri F,
Pera M,
Phelan R,
Rosental B,
Ryder O,
Sukparangsi W,
Sullivan G,
Tay N,
Traylor-Knowles N,
Walker S,
Weberling A,
Whitworth D,
Williams S,
Wojtusik J,
Wu J,
Ying Q,
Zwaka T,
Kohler T.
Advancing stem cell technologies for conservation of wildlife biodiversity. Development. 2024;151(20):dev203116
Keywords
JMG, Animals, Animals, Wild, Biodiversity, Conservation of Natural Resources, Stem Cells, Stem Cell Research
JAX Source
Development. 2024;151(20):dev203116
ISSN
1477-9129
PMID
39382939
DOI
https://doi.org/10.1242/dev.203116
Abstract
Wildlife biodiversity is essential for healthy, resilient and sustainable ecosystems. For biologists, this diversity also represents a treasure trove of genetic, molecular and developmental mechanisms that deepen our understanding of the origins and rules of life. However, the rapid decline in biodiversity reported recently foreshadows a potentially catastrophic collapse of many important ecosystems and the associated irreversible loss of many forms of life on our planet. Immediate action by conservationists of all stripes is required to avert this disaster. In this Spotlight, we draw together insights and proposals discussed at a recent workshop hosted by Revive & Restore, which gathered experts to discuss how stem cell technologies can support traditional conservation techniques and help protect animal biodiversity. We discuss reprogramming, in vitro gametogenesis, disease modelling and embryo modelling, and we highlight the prospects for leveraging stem cell technologies beyond mammalian species.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.