Workshop Report-Heterogeneity and Successful Aging Part I: Heterogeneity in Aging-Challenges and Opportunities.

Document Type

Article

Publication Date

3-7-2025

Publication Title

The journals of gerontology. Series A, Biological sciences and medical sciences

Keywords

JMG, Aging, Humans, National Institute on Aging (U.S.), United States, Aged, Biomedical Research

JAX Source

Biol Sci Med Sci. 2025;80(4):glaf023.

Volume

80

Issue

4

ISSN

1758-535X

PMID

40052564

DOI

https://doi.org/10.1093/gerona/glaf023

Abstract

Historically, aging research has focused primarily on the study of differences in means of varied measures obtained at different ages. However, growing evidence has shown that for many parameters, variability in measurements obtained both between- and within-age groups increases with aging. Moreover, growing heterogeneity may become especially apparent when examined via longitudinal as opposed to cross-sectional aging data. Efforts to deconvolute and better understand such heterogeneity present remarkable translational opportunities for developing targeted and more effective interventions into aging. Here, we present Part I, a summary of the NIA Heterogeneity and Successful Aging workshop virtually held in May 2023.

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