Is RNA editing involved in the full recovery of kidneys in Black Bears after hibernation.
Document Type
Article
Publication Date
Summer 2017
JAX Location
In: Student Reports, Summer 2017, Jackson Laboratory
Sponsor
Dr. Ron Korstanje
Abstract
My research focused on determining whether RNA editing was responsible for the differences in base pairs between the Black Bear genome sequence and the RNA sequence in the kidney. Thirty-five cases of RNA editing were observed in Dr. Ron Korstanje's lab by analyzing and comparing the RNA and genome sequences for a change of base pairs alone. In this study, I utilized Integrative Genomics Viewer, Polymerase Chain reactions, Electrophoresis Gels, and Sanger Sequencing on three Fall and three Spring black bear samples to confirm eight cases of RNA editing. I did so in an attempt to fmd a correlation between the process of RNA editing and the Black Bear's ability to reverse kidney damage after hibernation.
Recommended Citation
Neptune-Bear, Selena, "Is RNA editing involved in the full recovery of kidneys in Black Bears after hibernation." (2017). Summer and Academic Year Student Reports. 2589.
https://mouseion.jax.org/strp/2589