Most Popular Papers*

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A missense mutation in Pitx2 leads to early-onset glaucoma via NRF2-YAP1 axis.
Yeming Yang, Xiao Li, Jieping Wang, Junkai Tan, Bernie Fitzmaurice, Patsy M. Nishina, Kuanxiang Sun, Wanli Tian, Wenjing Liu, Xuyang Liu, Bo Chang, and Xianjun Zhu

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A Microbe Associated with Sleep Revealed by a Novel Systems Genetic Analysis of the Microbiome in Collaborative Cross Mice.
Jason A. Bubier, Vivek M. Philip, Christopher Quince, James Campbell, Yanjiao Zhou, Tatiana Vishnivetskaya, Suman Duvvuru, Rachel Hageman Blair, Juliet Ndukum, Kevin D Donohue, Carmen M Foster, David J Mellert, George M. Weinstock, Cymbeline T Culiat, Bruce F O'Hara, Anthony V Palumbo, Mircea Podar, and Elissa J Chesler

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Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H.
Kevin P Kotredes, Adrian Oblak, Ravi S Pandey, Peter Bor-Chian Lin, Dylan Garceau, Harriet M. Jackson, Asli Uyar, Rita O'Rourke, Sarah O'Rourke, Cynthia Ingraham, Daria Bednarycek, Melisa Belanger, Zackary Cope, Kate E Foley, Benjamin A Logsdon, Lara M Mangravite, Stacey J Sukoff Rizzo, Paul R Territo, Gregory W. Carter, Michael Sasner, Bruce T Lamb, and Gareth R Howell

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CXCL1: A new diagnostic biomarker for human tuberculosis discovered using Diversity Outbred mice.
Deniz Koyuncu, Muhammad Khalid Khan Niazi, Thomas Tavolara, Claudia Abeijon, Melanie L Ginese, Yanghui Liao, Carolyn Mark, Aubrey Specht, Adam C Gower, Blanca I Restrepo, Daniel M Gatti, Igor Kramnik, Metin Gurcan, Bülent Yener, and Gillian Beamer

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Cultivation of common bacterial species and strains from human skin, oral, and gut microbiota.
Elizabeth Fleming, Victor Pabst, Zoe Scholar, Ruoyun Xiong, Anita Y Voigt, Wei Zhou, Amelia Hoyt, Rachel Hardy, Anna Peterson, Ryan Beach, Yvette Ondouah-Nzutchi, Jinhong Dong, Lucinda Bateman, Suzanne D Vernon, and Julia Oh

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An effective biomedical document classification scheme in support of biocuration: addressing class imbalance.
Xiangying Jiang, Martin Ringwald, Judith A. Blake, Cecilia Arighi, Gongbo Zhang, and Hagit Shatkay

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Ultrastructural visualization of 3D chromatin folding using volume electron microscopy and DNA in situ hybridization.
Paweł Trzaskoma, Błażej Ruszczycki, Byoungkoo Lee, Katarzyna K Pels, Katarzyna Krawczyk, Grzegorz Bokota, Andrzej A Szczepankiewicz, Jesse Aaron, Agnieszka Walczak, Małgorzata A Śliwińska, Adriana Magalska, Michal Kadlof, Artur Wolny, Zofia Parteka, Sebastian Arabasz, Magdalena Kiss-Arabasz, Dariusz Plewczyński, Yijun Ruan, and Grzegorz M Wilczyński

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The case for open science: rare diseases.
Yaffa R Rubinstein, Peter N Robinson, William A Gahl, Paul Avillach, Gareth Baynam, Helene Cederroth, Rebecca M Goodwin, Stephen C Groft, Mats G Hansson, Nomi L Harris, Vojtech Huser, Deborah Mascalzoni, Julie A McMurry, Matthew Might, Christoffer Nellaker, Barend Mons, Dina N Paltoo, Jonathan Pevsner, Manuel Posada, Alison P Rockett-Frase, Marco Roos, Tamar B Rubinstein, Domenica Taruscio, Esther van Enckevort, and Melissa A Haendel

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Integrated analysis of the molecular pathogenesis of FDXR-associated disease.
Jesse D Slone, Li Yang, Yanyan Peng, Luis F Queme, Belinda S. Harris, Stacey J Sukoff Rizzo, Torrian Green, Jennifer L Ryan, Michael P Jankowski, Laura G Reinholdt, and Taosheng Huang

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