2,4-diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl] Quinazoline (tmq), potent non-classical folate antagonist inhibitor. I. Effect on dihydrofolate reductase and growth of rodent tumors in vitro and in vivo.

Authors

J R. Bertino
W L. Sawicki
B A. Moroson
E F. Elslager

Document Type

Article

Publication Date

1978

Keywords

Chemotherapy:, Neoplasm:, Tissue Culture:, Types of Tumors:, Transplantable Tumors: SAR-180, L 1210, L 5178(Y), B16

Original Citation

Biochem Pharmacol 1978; 28:1983-7.