Genetic control of cross-reactive cytotoxic T-lymphocyte responses to a BALB/c tumor.
Antibodies-Neoplasm: ge, Cross-Reactions, Genes-Immune-Response, Genes-Structural, Hair-Color, Linkage-(Genetics), Mice, Mice-Inbred-BALB-C: ge, Mice-Inbred-DBA: ge, Neoplasms-Experimental: im, Phenotype, Plasmacytoma: im, SUPPORT-NON-U-S-GOVT, SUPPORT-U-S-GOVT-P-H-S
Immunogenetics. 1981; 14(3-4):263-72.
Using a segregation analysis we have determined that the cross-reactive response to the DBA/2 tumor P815 by CTL from BALB/c mice immunized with a BALB/c plasmacytoma (MOPC-167) is controlled by a single gene. The gene responsible is closely linked to the dilute coat color locus on chromosome 9. In contrast, the cross-reactive response to the DBA/2 tumor L5178Y by DBA/2 anti-MOPC-167 CTL appears to be controlled by two or more genes.
Russell, J H.; Dobos, C B.; Graff, R J.; and Taylor, B A., " Genetic control of cross-reactive cytotoxic T-lymphocyte responses to a BALB/c tumor." (1981). Faculty Research 1980 - 1989. 114.
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