Faculty Research 1980 - 1989

Title

Development of Dickie's small eye: an early lethal mutation in the house mouse.

Document Type

Article

Publication Date

1980

Keywords

Embryo, Eye: ab, Genes-Lethal, Heterozygote, Homozygote, Mice, Mice-Mutant-Strains, Time-Factors

JAX Source

Anat-Embryol-(Berl). 1980; 161(1):115-20.

Abstract

Mice heterozygous for Dickie's small eye (Dey) are small and have malformed eyes (Theiler et al. 1978). The development of homozygous Dey/Dey was more difficult to analyze than heterozygous Dey/+. This investigation to identify the homozygotes and to distinguish them from Dey/+ and +/+ resorptions. Such a distinction was possible only when enough specimens were available. The mutants are poor breeders and the collection of the necessary material has taken several years.

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