Faculty Research 1980 - 1989

Amyloidosis development in LLC mice.

Document Type

Article

Publication Date

1984

Keywords

Amyloidosis: pa, Animal, Gold, Mice, Mice-Inbred-Strains, Microscopy-Electron, Spleen: ul, SUPPORT-U-S-GOVT-P-H-S

First Page

339

Last Page

346

JAX Location

89

JAX Source

Exp-Cell-Biol. 1984; 52(6):339-46.

Grant

AG02122

Abstract

Using electron microscopy and the protein A-gold labelling technique we studied amyloidosis in the LLC mice, an inbred strain developing amyloidosis spontaneously. We found that the reticular cells lining around the sinuses in the red pulp of the spleen were converted to amyloid. Evidence suggests that the amyloid originates in the cells themselves. The process of amyloid formation is discussed.

Please contact the Joan Staats Library for information regarding this document.

Share

COinS