Faculty Research 1980 - 1989
The structural gene for F liver protein (Flp) maps to chromosome 5 of the mouse.
Document Type
Article
Publication Date
1987
Keywords
Chromosome-Mapping, Genes-Structural, Genetic-Marker, Isoantigens: ge, Liver: im, Mice, Mice-Inbred-Strains, Species-Specificity, SUPPORT-U-S-GOVT-P-H-S
First Page
356
Last Page
358
JAX Source
Immunogenetics. 1987; 26(6):356-8.
Grant
GM18684
Abstract
The BXD and AKXL panels of recombinant inbred mouse strains have been typed for the F liver protein alloantigen. The structural gene for F liver protein gene (Flp) is placed on the distal part of chromosome 5, between the known markers Bcd-1 and Gus-s. This excludes the possibility that F liver protein is a major histocompatibility complex molecule, and in turn raises a question about the uniqueness of F and certain other proteins as purgers of self-reactivity among T but not B cells. The typed RI strains have then been used for the immunogenetic studies presented in the succeeding article.
Recommended Citation
Winchester G,
Mitchison NA,
Taylor BA.
The structural gene for F liver protein (Flp) maps to chromosome 5 of the mouse. Immunogenetics. 1987; 26(6):356-8.