Faculty Research 1990 - 1999
Genomic organization, expression and chromosomal localization of the mouse Slug (Slugh) gene.
Document Type
Article
Publication Date
1998
First Page
251
Last Page
254
JAX Source
Biochim Biophys Acta 1998 Nov 26;1443(1-2):251-4
Grant
CA34196/CA/NCI, RO1HD34883/HD/NICHD
Abstract
The Slug gene encodes a zinc finger protein implicated in the generation and migration of neural crest cells in several vertebrate species. Here we describe the genomic organization and chromosomal localization of the mouse Slug (Slugh) gene. The mouse Slug gene consists of three exons spanning approx. 4 kb. Northern blot analysis of RNA isolated from several tissues of adult mice revealed the presence of a single 2.1 kb transcript. The chromosomal location of mouse Slug was determined by interspecific backcross analysis. The mapping results indicated that Slugh is located in the proximal region of mouse chromosome 16.
Recommended Citation
Jiang R,
Norton CR,
Copeland NG,
Gilbert DJ,
Jenkins NA,
Gridley T.
Genomic organization, expression and chromosomal localization of the mouse Slug (Slugh) gene. Biochim Biophys Acta 1998 Nov 26;1443(1-2):251-4