Pathbase: a new reference resource and database for laboratory mouse pathology.
Document Type
Article
Publication Date
2004
Keywords
Databases-Factual, Genotype, Information-Storage-and-Retrieval, Internet, Mice, Mutation, Pathology, Phenotype, Research-Support-Non-U, S, -Gov't, Vocabulary-Controlled
First Page
525
Last Page
528
JAX Source
Radiat Prot Dosimetry 2004; 112(4):525-8.
Abstract
Pathbase (http://www.pathbase.net) is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of mutant or genetically engineered mice and their background strains. The metadata for the images, which allows retrieval and interoperability with other databases, is derived from a series of orthogonal ontologies and controlled vocabularies. One of these controlled vocabularies, MPATH, was developed by the Pathbase Consortium as a formal description of the content of mouse histopathological images. The database currently has over 1000 images on-line with 2000 more under curation and presents a paradigm for the development of future databases dedicated to aspects of experimental biology.
Recommended Citation
Schofield PN,
Bard JB,
Boniver J,
Covelli V,
Delvenne P,
Engstrom W,
Gruenberger M,
Hopewell JW,
Mancuso M,
Mothersill C,
Quintanilla ML,
Rozell B,
Sariola H,
Sundberg JP,
Ward A.
Pathbase: a new reference resource and database for laboratory mouse pathology. Radiat Prot Dosimetry 2004; 112(4):525-8.