Crossover interference underlies sex differences in recombination rates.

Authors

P M. PetkovFollow
K W. Broman
J P. Szatkiewicz
K PaigenFollow

Document Type

Article

Publication Date

2007

First Page

539

Last Page

542

JAX Source

Trends Genet 2007 Nov; 23(11):539-42.

Abstract

In many organisms, recombination rates differ between the two sexes. Here we show that in mice, this is because of a shorter genomic interference distance in females than in males, measured in Mb. However, the interference distance is the same in terms of bivalent length. We propose a model in which the interference distance in the two sexes reflects the compaction of chromosomes at the pachytene stage of meiosis.

Recommended Citation

Petkov PM, Broman KW, Szatkiewicz JP, Paigen K. Crossover interference underlies sex differences in recombination rates. Trends Genet 2007 Nov; 23(11):539-42.