Naive application of permutation testing leads to inflated type I error rates.
Document Type
Article
Publication Date
2008
Keywords
Models-Statistical, Research-Design
First Page
609
Last Page
610
JAX Source
Genetics 2008 Jan; 178(1):609-10.
Abstract
Failure to account for family structure within populations or in complex mating designs via uninformed applications of permutation testing will lead to inflated type I error rates. Careful consideration of the design factors is essential since some situations allow several valid permutation strategies, and the choice that maximizes statistical power will not always be intuitive.
Recommended Citation
Churchill GA,
Doerge RW.
Naive application of permutation testing leads to inflated type I error rates. Genetics 2008 Jan; 178(1):609-10.
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