Hematopoietic cell types: Prototype for a revised cell ontology.
Document Type
Article
Publication Date
2009
Book Title
ICBO:International Conference on Biomedical Ontology.
First Page
23
Last Page
26
JAX Location
see Reprint Collection, a pdf is available.
JAX Source
IN:ICBO:International Conference on Biomedical Ontology 2009:23-26.
Abstract
The Cell Ontology (CL) aims for the representation of in vivo and in vitro cell types from all of biology. The CL is a candidate reference ontology of the OBO Foundry and requires extensive revision to bring it up to current standards for biomedical ontologies, both in its structure and its coverage of various subfields of biology. We have now addressed the specific content of one area of the CL, the section of the ontology dealing with hematopoietic cells. This section has been extensively revised to improve its content and eliminate multiple inheritance in the asserted hierarchy, and the groundwork has been laid for structuring the hematopoietic cell type terms as cross-products incorporating logical definitions built from relationships to external ontologies, such as the Protein Ontology and the Gene Ontology. The methods and improvements to the CL in this area represent a paradigm for improvement of the entire ontology over time.
Recommended Citation
Diehl AD,
Augustine AD,
Blake JA,
Cowell LG,
Gold ES,
Gondre LT,
Masci AM,
Meehan TF,
Morel PA,
Nijnik A,
et a.
Hematopoietic cell types: Prototype for a revised cell ontology. IN:ICBO:International Conference on Biomedical Ontology 2009:23-26.