Mapping of rabbit chromosome 1 markers generated from a microsatellite-enriched chromosome-specific library.

Document Type

Article

Publication Date

2001

Keywords

Chromosome-Mapping, Crosses-Genetic, Dinucleotide-Repeats, Female, Genomic-Library, Male, Microsatellite-Repeats, Polymorphism-(Genetics), Rabbits

First Page

308

Last Page

312

JAX Location

see Journal Stacks

JAX Source

Anim Genet 2001 Oct; 32(5):308-12.

Abstract

A genomic DNA library was produced from flow-sorted rabbit chromosome 1 and enriched for fragments containing CA-repeats. Clones containing CA-repeats were identified and primers for amplification of the microsatellite were developed after sequencing the clone. The degree of polymorphism was tested in rabbits from different breeds. This approach identified 12 microsatellite markers which could be used for studying linkage relationships in the progeny of an F(2)-intercross: (AX/JUxIIIVO/JU) F(2), and two backcrosses: (OS/JxX/J)X/J and (WH/JxX/J)X/J. Seven of these markers were mapped on chromosome 1.

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