Statistical tests for differential expression in cDNA microarray experiments.
Document Type
Article
Publication Date
2003
Keywords
Gene-Expression-Profiling, Matched-Pair-Analysis, Oligonucleotide-Array-Sequence-Analysis, Statistics
First Page
210
Last Page
210
JAX Location
see 2003 Staff CD - Library Office
JAX Source
Genome Biol 2003; 4(4):210.
Abstract
Extracting biological information from microarray data requires appropriate statistical methods. The simplest statistical method for detecting differential expression is the t test, which can be used to compare two conditions when there is replication of samples. With more than two conditions, analysis of variance (ANOVA) can be used, and the mixed ANOVA model is a general and powerful approach for microarray experiments with multiple factors and/or several sources of variation.
Recommended Citation
Cui X,
Churchill GA.
Statistical tests for differential expression in cDNA microarray experiments. Genome Biol 2003; 4(4):210.