Statistical tests for differential expression in cDNA microarray experiments.
Gene-Expression-Profiling, Matched-Pair-Analysis, Oligonucleotide-Array-Sequence-Analysis, Statistics
see 2003 Staff CD - Library Office
Genome Biol 2003; 4(4):210.
Extracting biological information from microarray data requires appropriate statistical methods. The simplest statistical method for detecting differential expression is the t test, which can be used to compare two conditions when there is replication of samples. With more than two conditions, analysis of variance (ANOVA) can be used, and the mixed ANOVA model is a general and powerful approach for microarray experiments with multiple factors and/or several sources of variation.
Cui, X and Churchill, G A., " Statistical tests for differential expression in cDNA microarray experiments." (2003). Faculty Research 2000 - 2009. 545.