Quantitative PCR genotyping assay for the Ts65Dn mouse model of Down syndrome.
Document Type
Article
Publication Date
2003
First Page
1170
Last Page
1178
JAX Location
see Journal stacks
JAX Source
Biotechniques 2003 Dec; 35(6):1170-4, 1176, 1178.
Abstract
The Ts65Dn mouse is a segmentally trisomic model for Down syndrome. Until now, Ts65Dn mice have been identified by the laborious methods of either chromosomal analysis of cultured peripheral lymphocytes or fluorescent in situ hybridization (FISH). We report here a quantitative PCR method for genotyping Ts65Dn mice, as well as a phenotypic description for visually preclassifying mice to be genotyped.
Recommended Citation
Liu DP,
Schmidt C,
Billings T,
Davisson MT.
Quantitative PCR genotyping assay for the Ts65Dn mouse model of Down syndrome. Biotechniques 2003 Dec; 35(6):1170-4, 1176, 1178.
COinS