Implementing large-scale ENU mutagenesis screens in North America.
Document Type
Article
Publication Date
2004
Keywords
Disease-Models-Animal, Ethylnitrosourea, Mice, Mutation, National-Institutes-of-Health-(U, S, ), Nervous-System-Diseases, Phenotype, United-States
First Page
51
Last Page
64
JAX Source
Genetica 2004 Sep; 122(1):51-64
Abstract
A step towards annotating the mouse genome is to use forward genetics in phenotype-driven screens to saturate the genome with mutations. The purpose of this article is to highlight the new projects in North America that are focused on isolating mouse mutations after ENU mutagenesis and phenotype screening.
Recommended Citation
Clark AT,
Goldowitz D,
Takahashi JS,
Vitaterna MH,
Siepka SM,
Peters LL,
Frankel WN,
Carlson GA,
Rossant J,
Nadeau JH,
Justice MJ.
Implementing large-scale ENU mutagenesis screens in North America. Genetica 2004 Sep; 122(1):51-64