The IKMC web portal: a central point of entry to data and resources from the International Knockout Mouse Consortium.
Document Type
Article
Publication Date
2011
Keywords
Animals, Databases-Genetic, Gene-Targeting, Genetic-Vectors, Genomics, Internet, Mice, Mice-Knockout, Molecular-Sequence-Annotation, User-Computer-Interface
JAX Source
Nucleic Acids Res 2011; 39(Database issue):D849-55.
Abstract
The International Knockout Mouse Consortium (IKMC) aims to mutate all protein-coding genes in the mouse using a combination of gene targeting and gene trapping in mouse embryonic stem (ES) cells and to make the generated resources readily available to the research community. The IKMC database and web portal (www.knockoutmouse.org) serves as the central public web site for IKMC data and facilitates the coordination and prioritization of work within the consortium. Researchers can access up-to-date information on IKMC knockout vectors, ES cells and mice for specific genes, and follow links to the respective repositories from which corresponding IKMC products can be ordered. Researchers can also use the web site to nominate genes for targeting, or to indicate that targeting of a gene should receive high priority. The IKMC database provides data to, and features extensive interconnections with, other community databases.
Recommended Citation
Ringwald M,
Iyer V,
Mason JC,
Stone KR,
Tadepally HD,
Kadin JA,
Bult CJ,
Eppig JT,
et a.
The IKMC web portal: a central point of entry to data and resources from the International Knockout Mouse Consortium. Nucleic Acids Res 2011; 39(Database issue):D849-55.