Notch Signaling during Oogenesis in Drosophila melanogaster.
Document Type
Article
Publication Date
1-1-2012
JAX Source
Genet Res Int 2012; 2012:648207.
PMID
22720165
Volume
2012
First Page
648207
Last Page
648207
ISSN
2090-3162
Abstract
The Notch signaling pathway is an evolutionarily conserved intercellular signaling mechanism that is required for embryonic development, cell fate specification, and stem cell maintenance. Discovered and studied initially in Drosophila melanogaster, the Notch pathway is conserved and functionally active throughout the animal kingdom. In this paper, we summarize the biochemical mechanisms of Notch signaling and describe its role in regulating one particular developmental pathway, oogenesis in Drosophila.
Recommended Citation
Xu J,
Gridley T.
Notch Signaling during Oogenesis in Drosophila melanogaster. Genet Res Int 2012; 2012:648207.
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