Cholesterol metabolism and Rett syndrome pathogenesis.

Document Type

Article

Publication Date

9-2013

JAX Source

Nat Genet 2013 Sep; 45(9):965-7.

Volume

45

Issue

9

First Page

965

Last Page

967

ISSN

1546-1718

PMID

23985682

Abstract

Rett syndrome is caused by mutations in the gene encoding the transcriptional regulator MECP2. A new study demonstrates that cholesterol homeostasis is disrupted in Mecp2 mutant mice and suggests new therapeutic options for this disease. Nat Genet 2013 Sep; 45(9):965-7.

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