Cholesterol metabolism and Rett syndrome pathogenesis.
Nat Genet 2013 Sep; 45(9):965-7.
Rett syndrome is caused by mutations in the gene encoding the transcriptional regulator MECP2. A new study demonstrates that cholesterol homeostasis is disrupted in Mecp2 mutant mice and suggests new therapeutic options for this disease. Nat Genet 2013 Sep; 45(9):965-7.
Nagy, Gabor and Ackerman, Susan L., "Cholesterol metabolism and Rett syndrome pathogenesis." (2013). Faculty Research 2013. 145.