Mouse Genome Informatics (MGI): reflecting on 25 years.

Authors

Janan T. Eppig, The Jackson LaboratoryFollow
Joel E Richardson, The Jackson LaboratoryFollow
James A. Kadin, The Jackson LaboratoryFollow
Martin Ringwald, The Jackson LaboratoryFollow
Judith A. Blake, The Jackson LaboratoryFollow
Carol J. Bult, The Jackson LaboratoryFollow

Document Type

Article

Publication Date

8-2015

JAX Source

Mamm Genome 2015 Aug; 26(7-8):272-84.

Volume

26

Issue

7-8

First Page

272

Last Page

284

ISSN

1432-1777

PMID

26238262

Grant

HG000330, HD062499, CA089713, HG004834, OD011190, GM080646

Abstract

From its inception in 1989, the mission of the Mouse Genome Informatics (MGI) resource remains to integrate genetic, genomic, and biological data about the laboratory mouse to facilitate the study of human health and disease. This mission is ever more feasible as the revolution in genetics knowledge, the ability to sequence genomes, and the ability to specifically manipulate mammalian genomes are now at our fingertips. Through major paradigm shifts in biological research and computer technologies, MGI has adapted and evolved to become an integral part of the larger global bioinformatics infrastructure and honed its ability to provide authoritative reference datasets used and incorporated by many other established bioinformatics resources. Here, we review some of the major changes in research approaches over that last quarter century, how these changes are reflected in the MGI resource you use today, and what may be around the next corner. Mamm Genome 2015 Aug; 26(7-8):272-84.

Recommended Citation

Eppig JT, Richardson J, Kadin JA, Ringwald M, Blake JA, Bult CJ. Mouse Genome Informatics (MGI): reflecting on 25 years. Mamm Genome 2015 Aug; 26(7-8):272-84.