Submissions from 2015
A novel patient-derived tumorgraft model with TRAF1-ALK anaplastic large-cell lymphoma translocation., F Abate, M Todaro, J-A van der Krogt, M Boi, I Landra, R Machiorlatti, F Tabbò, K Messana, C Abele, A Barreca, D Novero, M Gaudiano, S Aliberti, F Di Giacomo, T Tousseyn, E Lasorsa, R Crescenzo, L Bessone, E Ficarra, A Acquaviva, A Rinaldi, M Ponzoni, D L Longo, S Aime, M Cheng, B Ruggeri, P P Piccaluga, S Pileri, E Tiacci, B Falini, B Pera-Gresely, L Cerchietti, J Iqbal, W C Chan, Leonard D. Shultz, I Kwee, R Piva, I Wlodarska, R Rabadan, F Bertoni, and G Inghirami
Analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms., Alexej Abyzov, Shantao Li, Daniel Rhee Kim, Marghoob Mohiyuddin, Adrian M Stütz, Nicholas F Parrish, Xinmeng Jasmine Mu, Wyatt Clark, Ken Chen, Matthew Hurles, Jan O Korbel, Hugo Y K Lam, Charles Lee, and Mark B Gerstein
Aging research using mouse models., Cheryl L. Ackert-Bicknell, Laura C. Anderson, Susan Sheehan, Warren G. Hill, Bo Chang, Gary A. Churchill, Elissa J. Chesler, Ron Korstanje, and Luanne L. Peters
Development and validation of the JAX Cancer Treatment Profile™ for detection of clinically actionable mutations in solid tumors., Guruprasad Ananda, Susan Mockus, Micaela Lundquist, Vanessa Spotlow, Allen K. Simons, Talia Mitchell, Grace Stafford, Vivek M. Philip, Timothy M. Stearns, Anuj Srivastava, Mary Barter, Lucy B. Rowe, Joan Malcolm, Carol J. Bult, Radha Krishna Murthy Karuturi, Karen Rasmussen, and Douglas Hinerfeld
Identification of CD34+ and CD34- leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemia., Yuki Aoki, Takashi Watanabe, Yoriko Saito, Yoko Kuroki, Atsushi Hijikata, Masatoshi Takagi, Daisuke Tomizawa, Mariko Eguchi, Minenori Eguchi-Ishimae, Akiko Kaneko, Rintaro Ono, Kaori Sato, Nahoko Suzuki, Saera Fujiki, Katsuyoshi Koh, Eiichi Ishii, Leonard D. Shultz, Osamu Ohara, Shuki Mizutani, and Fumihiko Ishikawa
Consensus nomenclature for CD8(+) T cell phenotypes in cancer., Lionel Apetoh, Mark J Smyth, Charles G Drake, Jean-Pierre Abastado, Ron N Apte, Maha Ayyoub, Jean-Yves Blay, Marc Bonneville, Lisa H Butterfield, Anne Caignard, Chiara Castelli, Federica Cavallo, Esteban Celis, Lieping Chen, Mario P Colombo, Begoña Comin-Anduix, Georges Coukos, Madhav V Dhodapkar, Glenn Dranoff, Ian H Frazer, Wolf-Hervé Fridman, Dmitry I Gabrilovich, Eli Gilboa, Sacha Gnjatic, Dirk Jäger, Pawel Kalinski, Howard L Kaufman, Rolf Kiessling, John Kirkwood, Alexander Knuth, Roland Liblau, Michael T Lotze, Enrico Lugli, Francesco Marincola, Ignacio Melero, Cornelis J Melief, Thorsten R Mempel, Elizabeth A Mittendorf, Kunle Odun, Willem W Overwijk, Anna Karolina Palucka, Giorgio Parmiani, Antoni Ribas, Pedro Romero, Robert D Schreiber, Gerold Schuler, Pramod K Srivastava, Eric Tartour, Danila Valmori, Sjoerd H van der Burg, Pierre van der Bruggen, Benoît J van den Eynde, Ena Wang, Weiping Zou, Theresa L Whiteside, Daniel E Speiser, Drew M Pardoll, Nicholas P Restifo, and Ana C Anderson
A Network Biology Approach to Denitrification in Pseudomonas aeruginosa., Seda Arat, George S Bullerjahn, and Reinhard Laubenbacher
Independent Neuronal Origin of Seizures and Behavioral Comorbidities in an Animal Model of a Severe Childhood Genetic Epileptic Encephalopathy., Samuel K. Asinof, Stacey J. Sukoff Rizzo, Alexandra R Buckley, Barbara J. Beyer, Verity A. Letts, Wayne N. Frankel, and Rebecca M. Boumil
A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome., Tin Aung, Mineo Ozaki, Takanori Mizoguchi, R Rand Allingham, Zheng Li, Aravind Haripriya, Satoko Nakano, Steffen Uebe, Jeffrey M. Harder, Anita S Y Chan, Mei Chin Lee, Kathryn P Burdon, Yury S Astakhov, Khaled K Abu-Amero, Juan C Zenteno, Yildirim Nilgün, Tomasz Zarnowski, Mohammad Pakravan, Leen Abu Safieh, Liyun Jia, Ya Xing Wang, Susan Williams, Daniela Paoli, Patricio G Schlottmann, Lulin Huang, Kar Seng Sim, Jia Nee Foo, Masakazu Nakano, Yoko Ikeda, Rajesh S Kumar, Morio Ueno, Shin-Ichi Manabe, Ken Hayashi, Shigeyasu Kazama, Ryuichi Ideta, Yosai Mori, Kazunori Miyata, Kazuhisa Sugiyama, Tomomi Higashide, Etsuo Chihara, Kenji Inoue, Satoshi Ishiko, Akitoshi Yoshida, Masahide Yanagi, Yoshiaki Kiuchi, Makoto Aihara, Tsutomu Ohashi, Toshiya Sakurai, Takako Sugimoto, Hideki Chuman, Fumihiko Matsuda, Kenji Yamashiro, Norimoto Gotoh, Masahiro Miyake, Sergei Y Astakhov, Essam A Osman, Saleh A Al-Obeidan, Ohoud Owaidhah, Leyla Al-Jasim, Sami Al Shahwan, Rhys A Fogarty, Paul Leo, Yaz Yetkin, Çilingir Oğuz, Mozhgan Rezaei Kanavi, Afsaneh Nederi Beni, Shahin Yazdani, Evgeny L Akopov, Kai-Yee Toh, Gareth R. Howell, Andrew C Orr, Yufen Goh, Wee Yang Meah, Su Qin Peh, Ewa Kosior-Jarecka, Urszula Lukasik, Mandy Krumbiegel, Eranga N Vithana, Tien Yin Wong, Yutao Liu, Allison E Ashley Koch, Pratap Challa, Robyn M Rautenbach, David A Mackey, Alex W Hewitt, Paul Mitchell, Jie Jin Wang, Ari Ziskind, Trevor Carmichael, Rangappa Ramakrishnan, Kalpana Narendran, Rangaraj Venkatesh, Saravanan Vijayan, Peiquan Zhao, Xueyi Chen, Dalia Guadarrama-Vallejo, Ching Yu Cheng, Shamira A Perera, Rahat Husain, Su-Ling Ho, Ulrich-Christoph Welge-Luessen, Christian Mardin, Ursula Schloetzer-Schrehardt, Axel M Hillmer, Stefan Herms, Susanne Moebus, Markus M Nöthen, Nicole Weisschuh, Rohit Shetty, Arkasubhra Ghosh, Yik Ying Teo, Matthew A Brown, Ignacio Lischinsky, Jonathan G Crowston, Michael Coote, Bowen Zhao, Jinghong Sang, Nihong Zhang, Qisheng You, Vera Vysochinskaya, Panayiota Founti, Anthoula Chatzikyriakidou, Alexandros Lambropoulos, Eleftherios Anastasopoulos, Anne L Coleman, M Roy Wilson, Douglas J Rhee, Jae Hee Kang, Inna May-Bolchakova, Steffen Heegaard, Kazuhiko Mori, Wallace L M Alward, Jost B Jonas, Liang Xu, Jeffrey M Liebmann, Balram Chowbay, Elke Schaeffeler, Matthias Schwab, Fabian Lerner, Ningli Wang, Zhenglin Yang, Paolo Frezzotti, Shigeru Kinoshita, John H Fingert, Masaru Inatani, Kei Tashiro, André Reis, Deepak P Edward, Louis R Pasquale, Toshiaki Kubota, Janey L Wiggs, Francesca Pasutto, Fotis Topouzis, Michael Dubina, Jamie E Craig, Nagahisa Yoshimura, Periasamy Sundaresan, Simon W M John, Robert Ritch, Michael A Hauser, and Chiea-Chuen Khor
Generation of β cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice., J Babad, G Mukherjee, A Follenzi, R Ali, B O Roep, Leonard D. Shultz, P Santamaria, O O Yang, H Goldstein, D L Greiner, and T P DiLorenzo
Deciphering the regulatory logic of an ancient, ultraconserved nuclear receptor enhancer module., Pia D Bagamasbad, Ronald M Bonett, Laurent Sachs, Nicolas Buisine, Samhitha Raj, Joseph R Knoedler, Yasuhiro Kyono, Yijun Ruan, Xiaoan Ruan, and Robert J Denver
PRDM9 Drives Evolutionary Erosion of Hotspots in Mus musculus through Haplotype-Specific Initiation of Meiotic Recombination., Christopher L. Baker, Shimpei Kajita, Michael Walker, Ruth L. Saxl, Narayanan Raghupathy, Kwangbom Choi, Petko M. Petkov, and Kenneth Paigen
Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots., Christopher L. Baker, Pavlina Petkova, Michael Walker, Petr Flachs, Ondrej Mihola, Zdenek Trachtulec, Petko M. Petkov, and Kenneth Paigen
Generation of Human B-Cell Lines Dependent on CD40-Ligation and Interleukin-4., Jacques Banchereau
Multicenter Comparison of Lung and Oral Microbiomes of HIV-infected and HIV-uninfected Individuals., James M Beck, Patrick D Schloss, Arvind Venkataraman, Homer Twigg, Kathleen A Jablonski, Frederic D Bushman, Thomas B Campbell, Emily S Charlson, Ronald G Collman, Kristina Crothers, Jeffrey L Curtis, Kimberly L Drews, Sonia C Flores, Andrew P Fontenot, Mary A Foulkes, Ian Frank, Elodie Ghedin, Laurence Huang, Susan V Lynch, Alison Morris, Brent E Palmer, Thomas M Schmidt, Erica Sodergren Weinstock, George M. Weinstock, and Vincent B Young
Finding mouse models of human lymphomas and leukemia's using the Jackson laboratory mouse tumor biology database., Dale A. Begley, John P. Sundberg, Debra M. Krupke, Steven B. Neuhauser, Carol J. Bult, Janan T. Eppig, Herbert C Morse, and Jerrold M Ward
Allele, phenotype and disease data at Mouse Genome Informatics: improving access and analysis., Susan M. Bello, Cynthia L. Smith, and Janan T. Eppig
Synapse Loss and Dendrite Remodeling in a Mouse Model of Glaucoma., Ryan H Berry, Juan Qu, Simon W M John, Gareth R. Howell, and Tatjana C Jakobs
Patient-specific driver gene prediction and risk assessment through integrated network analysis of cancer omics profiles., Denis Bertrand, Kern Rei Chng, Faranak Ghazi Sherbaf, Anja Kiesel, Burton K H Chia, Yee Yen Sia, Sharon K Huang, Dave S B Hoon, Edison T. Liu, Axel Hillmer, and Niranjan Nagarajan
Defining the three cell lineages of the human blastocyst by single-cell RNA-seq., Paul Blakeley, Norah M E Fogarty, Ignacio Del Valle, Sissy E Wamaitha, Tim Xiaoming Hu, Kay Elder, Philip Snell, Leila Christie, Paul Robson, and Kathy K Niakan
Systemic, postsymptomatic antisense oligonucleotide rescues motor unit maturation delay in a new mouse model for type II/III spinal muscular atrophy., Laurent P. Bogdanik, Melissa A. Osborne, Crystal Davis, Whitney P. Martin, Andrew Austin, Frank Rigo, C Frank Bennett, and Cathleen M. Lutz
Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database., Molly A. Bogue, Gary Churchill, and Elissa J. Chesler
Decreased HIV-Specific T-Regulatory Responses Are Associated with Effective DC-Vaccine Induced Immunity., Vedran Brezar, Nicolas Ruffin, Laura Richert, Mathieu Surenaud, Christine Lacabaratz, Karolina Palucka, Rodolphe Thiébaut, Jacques Banchereau, Yves Levy, and Nabila Seddiki
GeneWeaver: finding consilience in heterogeneous cross-species functional genomics data., Jason A. Bubier, Charles A Phillips, Michael A Langston, Erich J Baker, and Elissa J. Chesler
Xenopus tropicalis Genome Re-Scaffolding and Re-Annotation Reach the Resolution Required for In Vivo ChIA-PET Analysis., Nicolas Buisine, Xiaoan Ruan, Patrice Bilesimo, Alexis Grimaldi, Gladys Alfama, Pramila Ariyaratne, Fabianus Mulawadi, Jieqi Chen, Wing-Kin Sung, Edison T. Liu, Barbara A Demeneix, Yijun Ruan, and Laurent M Sachs
Mouse Tumor Biology (MTB): a database of mouse models for human cancer., Carol J. Bult, Debra M. Krupke, Dale A. Begley, Joel E Richardson, Steven Neuhauser, John P. Sundberg, and Janan T. Eppig
Coding and noncoding expression patterns associated with rare obesity-related disorders: Prader-Willi and Alstrom syndromes., Merlin G. Butler, Kun Wang, Jan D. Marshall, Juergen K. Naggert, Jasmine A. Rethmeyer, Sumedha S. Gunewardena, and Ann M. Manzardo
Diet dominates host genotype in shaping the murine gut microbiota., Rachel N Carmody, Georg K Gerber, Jesus M Luevano, Daniel M. Gatti, Lisa Somes, Karen L. Svenson, and Peter J Turnbaugh
BRENDA in 2015: exciting developments in its 25th year of existence., Antje Chang, Ida Schomburg, Sandra Placzek, Lisa Jeske, Marcus Ulbrich, Mei Xiao, Christoph W Sensen, and Dietmar Schomburg
Survey of the nob5 mutation in C3H substrains., Bo Chang
A laminin 511 matrix is regulated by TAZ and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells., Cheng Chang, Hira Lal Goel, Huijie Gao, Bryan Pursell, Leonard D. Shultz, Dale L Greiner, Sulev Ingerpuu, Manuel Patarroyo, Shiliang Cao, Elgene Lim, Junhao Mao, Karen Kulju McKee, Peter D Yurchenco, and Arthur M Mercurio
A novel vaccine for mantle cell lymphoma based on targeting cyclin D1 to dendritic cells via CD40., Jingtao Chen, Gerard Zurawski, Sandy Zurawski, Zhiqing Wang, Keiko Akagawa, Sangkon Oh, Ueno Hideki, Joseph Fay, Jacques Banchereau, Wenru Song, and Karolina Palucka
The pathogenesis of chronic eosinophilic esophagitis in SHARPIN-deficient mice., Syu-Jhe Chien, Kathleen A Silva, Victoria E. Kennedy, Harm HogenEsch, and John P. Sundberg
Genomic Alterations in the RB Pathway Indicate Prognostic Outcomes of Early-Stage Lung Adenocarcinoma., Seongmin Choi, Hyeong Ryul Kim, Chang Ohk Sung, Jongkyu Kim, Sukjun Kim, Sung-Min Ahn, Chang-Min Choi, Sung-Min Chun, Eun Kyung Choi, Sang-We Kim, Yong-Hee Kim, Ji-Young Lee, Joon Seon Song, Deokhoon Kim, Farhan Haq, Sun Young Lee, Jong-Eun Lee, Wang-Rim Jung, Hye Yoon Jang, Eunho Yang, Charles Lee, Eunsil Yu, Gu Kong, Daehyun Baek, and Se Jin Jang
Inherited CHST11/MIR3922 deletion is associated with a novel recessive syndrome presenting with skeletal malformation and malignant lymphoproliferative disease., Sameer S Chopra, Ignaty Leshchiner, Hatice Duzkale, Heather McLaughlin, Monica Giovanni, Chengsheng Zhang, Nathan Stitziel, Joyce Fingeroth, Robin M Joyce, Matthew Lebo, Heidi Rehm, Dana Vuzman, Richard Maas, Shamil R Sunyaev, Michael Murray, and Christopher A Cassa
Adult-onset type 1 diabetes patients display decreased IGRP-specific Tr1 cells in blood., Daisuke Chujo, Thien-Son Nguyen, Emile Foucat, Derek Blankenship, Jacques Banchereau, Gerald T Nepom, Damien Chaussabel, and Hideki Ueno
Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice., Rachel J Church, Daniel Mario Gatti, Thomas J Urban, Nanye Long, Xi Yang, Qiang Shi, J Scott Eaddy, Merrie Mosedale, Shawn Ballard, Gary A. Churchill, Victor Navarro, Paul B Watkins, David W Threadgill, and Alison H Harrill
Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation., Gayle B. Collin, Dirk Hubmacher, Jeremy R. Charette, Wanda L. Hicks, Lisa Stone, Minzhong Yu, Juergen K. Naggert, Mark P. Krebs, Neal S Peachey, Suneel S Apte, and Patsy M. Nishina
The Blood Transcriptome of Experimental Melioidosis Reflects Disease Severity and Shows Considerable Similarity with the Human Disease., Laura Conejero, Krzysztof Potempa, Christine M Graham, Natasha Spink, Simon Blankley, Francisco J Salguero, Rungnapa Pankla-Sranujit, Prasong Khaenam, Jacques F. Banchereau, Virginia Pascual, Damien Chaussabel, Ganjana Lertmemongkolchai, Anne O'Garra, and Gregory J Bancroft
Gene Ontology Consortium: going forward., Gene Ontology Consortium, Judith A. Blake, Karen R. Christie, Mary E. Dolan, Harold J. Drabkin, David P. Hill, Li Ni, Dmitry Sitnikov, and et .. al
Utilising the resources of the International Knockout Mouse Consortium: the Australian experience., Leanne M Cotton, Michelle L Meilak, Tanya Templeton, Jose G Gonzales, Arianna Nenci, Melissa Cooney, Dirk Truman, Fleur Rodda, Alyce Lynas, Elizabeth Viney, Nadia Rosenthal, Deborah M Bianco, Moira K O'Bryan, and Ian M Smyth
Convergent Mutations and Kinase Fusions Lead to Oncogenic STAT3 Activation in Anaplastic Large Cell Lymphoma., Ramona Crescenzo, Francesco Abate, Elena Lasorsa, Fabrizio Tabbo', Marcello Gaudiano, Nicoletta Chiesa, Filomena Di Giacomo, Elisa Spaccarotella, Luigi Barbarossa, Elisabetta Ercole, Maria Todaro, Michela Boi, Andrea Acquaviva, Elisa Ficarra, Domenico Novero, Andrea Rinaldi, Thomas Tousseyn, Andreas Rosenwald, Lukas Kenner, Lorenzo Cerroni, Alexander Tzankov, Maurilio Ponzoni, Marco Paulli, Dennis Weisenburger, Wing C Chan, Javeed Iqbal, Miguel A Piris, Alberto Zamo', Carmela Ciardullo, Davide Rossi, Gianluca Gaidano, Stefano Pileri, Enrico Tiacci, Brunangelo Falini, Leonard D. Shultz, Laurence Mevellec, Jorge E Vialard, Roberto Piva, Francesco Bertoni, Raul Rabadan, and Giorgio Inghirami
A novel allele of Alx4 results in reduced Fgf10 expression and failure of eyelid fusion in mice., Michelle Curtain, Caleb S Heffner, Dennis M Maddox, Polyxeni Gudis, Leah Rae Donahue, and Stephen A Murray
Kif18a is specifically required for mitotic progression during germ line development., Anne M Czechanski, Haein Kim, Candice Byers, Ian Greenstein, Jason Stumpff, and Laura G. Reinholdt
Metabolic stressors disrupt proteome homeostasis to suppress malignancy., Chengkai Dai
Suppression of the HSF1-mediated proteotoxic stress response by the metabolic stress sensor AMPK., Siyuan Dai, Zijian Tang, Junyue Cao, Wei Zhou, Huawen Li, Stephen B. Sampson, and Chengkai Dai
The Frequency-Response Electroretinogram Distinguishes Cone and Abnormal Rod Function in rd12 Mice., Xufeng Dai, Hua Zhang, Ying He, Yan Qi, Bo Chang, and Ji-Jing Pang
Enhanced GAB2 Expression Is Associated with Improved Survival in High-Grade Serous Ovarian Cancer and Sensitivity to PI3K Inhibition., Sally J Davis, Karen E Sheppard, Michael S Anglesio, Joshy George, Nadia Traficante, Sian Fereday, Maria P Intermaggio, Usha Menon, Aleksandra Gentry-Maharaj, Jan Lubinski, Jacek Gronwald, Celeste Leigh Pearce, Malcolm C Pike, Anna Wu, Stefan Kommoss, Jacobus Pfisterer, Andreas du Bois, Felix Hilpert, Susan J Ramus, David D L Bowtell, David G Huntsman, Richard B Pearson, Kaylene J Simpson, Ian G Campbell, and Kylie L Gorringe
Kidney adysplasia and variable hydronephrosis, a new mutation affecting the odd-skipped related 1 gene in the mouse, causes variable defects in kidney development and hydronephrosis., Muriel T. Davisson, Susan A. Cook, Ellen C. Akeson, Don Liu, Caleb Heffner, Polyxeni Gudis, Heather Fairfield, and Stephen A. Murray
Finding Our Way through Phenotypes., Andrew R Deans, Suzanna E Lewis, Eva Huala, Salvatore S Anzaldo, Michael Ashburner, James P Balhoff, David C Blackburn, Judith A. Blake, J Gordon Burleigh, Bruno Chanet, Laurel D Cooper, Mélanie Courtot, Sándor Csösz, Hong Cui, Wasila Dahdul, Sandip Das, T Alexander Dececchi, Agnes Dettai, Rui Diogo, Robert E Druzinsky, Michel Dumontier, Nico M Franz, Frank Friedrich, George V Gkoutos, Melissa Haendel, Luke J Harmon, Terry F Hayamizu, Yongqun He, Heather M Hines, Nizar Ibrahim, Laura M Jackson, Pankaj Jaiswal, Christina James-Zorn, Sebastian Köhler, Guillaume Lecointre, Hilmar Lapp, Carolyn J Lawrence, Nicolas Le Novère, John G Lundberg, James Macklin, Austin R Mast, Peter E Midford, István Mikó, Christopher J Mungall, Anika Oellrich, David Osumi-Sutherland, Helen Parkinson, Martín J Ramírez, Stefan Richter, Peter N Robinson, Alan Ruttenberg, Katja S Schulz, Erik Segerdell, Katja C Seltmann, Michael J Sharkey, Aaron D Smith, Barry Smith, Chelsea D Specht, R Burke Squires, Robert W Thacker, Anne Thessen, Jose Fernandez-Triana, Mauno Vihinen, Peter D Vize, Lars Vogt, Christine E Wall, Ramona L Walls, Monte Westerfeld, Robert A Wharton, Christian S Wirkner, James B Woolley, Matthew J Yoder, Aaron M Zorn, and Paula Mabee
Non-neutral evolution and reciprocal monophyly of two expressed Mhc class II B genes in Leach's storm-petrel., Donald C Dearborn, Andrea B Gager, Morgan E Gilmour, Andrew G McArthur, Douglas A Hinerfeld, and Robert A Mauck
Genetic properties of the MAGIC maize population: a new platform for high definition QTL mapping in Zea mays., Matteo Dell'Acqua, Daniel M. Gatti, Giorgio Pea, Federica Cattonaro, Frederik Coppens, Gabriele Magris, Aye L Hlaing, Htay H Aung, Hilde Nelissen, Joke Baute, Elisabetta Frascaroli, Gary A. Churchill, Dirk Inzé, Michele Morgante, and Mario Enrico Pè
STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection., Ludovic Desvignes, Carl Weidinger, Patrick Shaw, Martin Vaeth, Theo Ribierre, Menghan Liu, Tawania Fergus, Lina Kozhaya, Lauren McVoy, Derya Unutmaz, Joel D Ernst, and Stefan Feske
miRNA Nomenclature: A View Incorporating Genetic Origins, Biosynthetic Pathways, and Sequence Variants., T Desvignes, P Batzel, E Berezikov, K Eilbeck, Janan T. Eppig, Monica S. McAndrews, A Singer, and J H Postlethwait
Epileptic encephalopathy-causing mutations in DNM1 impair synaptic vesicle endocytosis., Ryan S Dhindsa, Shelton S Bradrick, Xiaodi Yao, Erin L Heinzen, Slave Petrovski, Brian J Krueger, Michael R Johnson, Wayne N Frankel, Steven Petrou, Rebecca M. Boumil, and David B Goldstein
Sex and strain influence attribution of incentive salience to reward cues in mice., Price E. Dickson, Kathryn A. McNaughton, Lingfeng Hou, Laura C. Anderson, Katie H Long, and Elissa J. Chesler
Association of novelty-related behaviors and intravenous cocaine self-administration in Diversity Outbred mice., Price E. Dickson, Juliet Ndukum, Troy Wilcox, James Clark, Brittany Roy, Lifeng Zhang, Yun Li, Da-Ting Lin, and Elissa J. Chesler
A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2., John P Didion, Andrew P Morgan, Amelia M-F Clayshulte, Rachel C Mcmullan, Liran Yadgary, Petko M. Petkov, Timothy A Bell, Daniel M. Gatti, James J Crowley, Kunjie Hua, David L Aylor, Ling Bai, Mark Calaway, Elissa J. Chesler, John E French, Thomas R Geiger, Terry J Gooch, Theodore Garland, Alison H Harrill, Kent Hunter, Leonard McMillan, Matt Holt, Darla R Miller, Deborah A O'Brien, Kenneth Paigen, Wenqi Pan, Lucy B. Rowe, Ginger D Shaw, Petr Simecek, Patrick F Sullivan, Karen L. Svenson, George M. Weinstock, David W Threadgill, Daniel Pomp, Gary Churchill, and Fernando Pardo-Manuel de Villena
Orthology for comparative genomics in the mouse genome database., Mary E. Dolan, Richard M. Baldarelli, Susan M. Bello, Li Ni, Monica S. McAndrews, Carol J. Bult, James A. Kadin, Joel E. Richardson, Martin Ringwald, Janan T. Eppig, and Judith A. Blake
Application of comparative biology in GO functional annotation: the mouse model., Harold J. Drabkin, Karen R. Christie, Mary E. Dolan, David P. Hill, Li Ni, Dmitry Sitnikov, and Judith A. Blake
Integrative Mouse and Human Studies Implicate ANGPT1 and ZBTB7C as Susceptibility Genes to Ischemic Injury., Rose Du, Jing Zhou, Svetlana Lorenzano, Wenming Liu, Nareerat Charoenvimolphan, Baogang Qian, Jun Xu, Jian Wang, Xinmu Zhang, Xin Wang, Annerose Berndt, William J Devan, Valerie J Valant, Jinyi Wang, Karen L Furie, Jonathan Rosand, Natalia Rost, Robert M Friedlander, Beverly Paigen, and Scott T Weiss
A brief review of recent Charcot-Marie-Tooth research and priorities., Sean Ekins, Nadia K Litterman, Renée J G Arnold, Robert W. Burgess, Joel S Freundlich, Steven J Gray, Joseph J Higgins, Brett Langley, Dianna E Willis, Lucia Notterpek, David Pleasure, Michael W Sereda, and Allison Moore
The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease., Janan T. Eppig, Judith A. Blake, Carol J. Bult, James A. Kadin, Joel E Richardson, and Mouse Genome Database Group
The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources., Janan T. Eppig, Howie Motenko, Joel E Richardson, Beverly Richards-Smith, and Cynthia Smith
Mouse Genome Informatics (MGI): reflecting on 25 years., Janan T. Eppig, Joel E Richardson, James A. Kadin, Martin Ringwald, Judith A. Blake, and Carol J. Bult
Mouse Genome Database: From sequence to phenotypes and disease models., Janan T. Eppig, Joel E Richardson, James A. Kadin, Cynthia L. Smith, Judith A. Blake, and Carol J. Bult
Retinoic acid metabolism proteins are altered in trichoblastomas induced by mouse papillomavirus 1., Helen B Everts, Liye Suo, Shinge Ghim, A Bennett Jenson, and John P. Sundberg
An Overview of Typical Infections of Research Mice: Health Monitoring and Prevention of Infection., James R. Fahey and Haiyan Olekszak
Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders., Heather Fairfield, Anuj Srivastava, Guruprasad Ananda, Rangjiao Liu, Martin Kircher, Anuradha Lakshminarayana, Belinda S. Harris, Son Yong Karst, Louise A. Dionne, Coleen C. Kane, Michelle Curtain, Melissa L. Berry, Patricia F. Ward-Bailey, Ian Greenstein, Candice Byers, Anne M. Czechanski, Jocelyn Sharp, Kristina Palmer, Polyxeni Gudis, Whitney Martin, Abby Tadenev, Laurent P. Bogdanik, C Herbert Pratt, Bo Chang, David G. Schroeder, Gregory A. Cox, Paul Cliften, Jeffrey Milbrandt, Stephen A. Murray, Robert W. Burgess, David E. Bergstrom, Leah Rae Donahue, Hanan Hamamy, Amira Masri, Federico A Santoni, Periklis Makrythanasis, Stylianos E Antonarakis, Jay Shendure, and Laura G. Reinholdt
Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities., Kimberly A Fernandes, Jeffrey M. Harder, Pete A. Williams, Rebecca L Rausch, Amy E Kiernan, K Saidas Nair, Michael G Anderson, Simon W M John, Gareth R Howell, and Richard T Libby
The mouse Gene Expression Database (GXD): New features and how to use them effectively., Jacqueline H. Finger, Constance M. Smith, Terry F. Hayamizu, Ingeborg J. McCright, Jingxia Xu, Janan T. Eppig, James A. Kadin, Joel E Richardson, and Martin Ringwald
Delivering HIV Gagp24 to DCIR Induces Strong Antibody Responses In Vivo., Anne-Laure Flamar, Vanessa Contreras, Sandra Zurawski, Monica Montes, Nathatlie Dereuddre-Bosquet, Frédéric Martinon, Jacques Banchereau, Roger Le Grand, Gerard Zurawski, and Yves Levy
Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity., John E French, Daniel M. Gatti, Daniel L Morgan, Grace E Kissling, Keith R Shockley, Gabriel A Knudsen, Kim G Shepard, Herman C Price, Deborah King, Kristine L Witt, Lars C Pedersen, Steven C. Munger, Karen L. Svenson, and Gary A. Churchill
Theory-of-mind in individuals with Alström syndrome is related to executive functions, and verbal ability., Hans-Erik Frölander, Claes Möller, Mary Rudner, Sushmit Mishra, Jan D. Marshall, Heather Piacentini, and Björn Lyxell
An ENU-induced mutation in the mouse Rnf212 gene is associated with male meiotic failure and infertility., Yasuhiro Fujiwara, Hirokazu Matsumoto, Kouyou Akiyama, Anuj Srivastava, Mizuho Chikushi, Mary Ann Handel, and Tetsuo Kunieda
Viral infection of engrafted human islets leads to diabetes., Glen R Gallagher, Michael A Brehm, Robert W Finberg, Bruce A Barton, Leonard D. Shultz, Dale L Greiner, Rita Bortell, and Jennifer P Wang
Cardiac-Restricted IGF-1Ea Overexpression Reduces the Early Accumulation of Inflammatory Myeloid Cells and Mediates Expression of Extracellular Matrix Remodelling Genes after Myocardial Infarction., Enrique Gallego-Colon, Robert D Sampson, Susanne Sattler, Michael D Schneider, Nadia Rosenthal, and Joanne Tonkin
Bridging tumor genomics to patient outcomes through an integrated patient-derived xenograft platform., David R Gandara, Philip C Mack, Carol J. Bult, Tianhong Li, Primo N Lara, Jonathan W Riess, Stephanie H Astrow, Regina Gandour-Edwards, David T Cooke, Ken Y Yoneda, Elizabeth H Moore, Chong-Xian Pan, Rebekah A Burich, Elizabeth A David, James G. Keck, Susan Airhart, Neal Goodwin, Ralph W de Vere White, and Edison T. Liu
Self-awareness in the retina., Andrew M. Garrett and Robert W. Burgess
Deletion of small ankyrin 1 (sAnk1) isoforms results in structural and functional alterations in aging skeletal muscle fibers., E Giacomello, M Quarta, C Paolini, R Squecco, P Fusco, L Toniolo, B Blaauw, L Formoso, D Rossi, C Birkenmeier, Luanne L. Peters, F Francini, F Protasi, C Reggiani, and V Sorrentino
Making the Leap from Research Laboratory to Clinic: Challenges and Opportunities for Next-Generation Sequencing in Infectious Disease Diagnostics., Brittany Goldberg, Heike Sichtig, Chelsie Geyer, Nathan Ledeboer, and George M. Weinstock
Histone modifications change with age, dietary restriction and rapamycin treatment in mouse brain., Huan Gong, Hong Qian, Robin Ertl, Clinton M. Astle, Gang G Wang, David E. Harrison, and Xiangru Xu
Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross., Lisa E Gralinski, Martin T Ferris, David L Aylor, Alan C Whitmore, Richard Green, Matthew B Frieman, Damon Deming, Vineet D Menachery, Darla R Miller, Ryan J Buus, Timothy A Bell, Gary A. Churchill, David W Threadgill, Michael G Katze, Leonard McMillan, William Valdar, Mark T Heise, Fernando Pardo-Manuel de Villena, and Ralph S Baric
Dominant, toxic gain-of-function mutations in gars lead to non-cell autonomous neuropathology., Stuart J Grice, James N Sleigh, William W Motley, Ji-Long Liu, Robert W. Burgess, Kevin Talbot, and M Zameel Cader
The Human Phenotype Ontology: Semantic Unification of Common and Rare Disease., Tudor Groza, Sebastian Köhler, Dawid Moldenhauer, Nicole Vasilevsky, Gareth Baynam, Tomasz Zemojtel, Lynn Marie Schriml, Warren Alden Kibbe, Paul N Schofield, Tim Beck, Drashtti Vasant, Anthony J Brookes, Andreas Zankl, Nicole L Washington, Christopher J Mungall, Suzanna E Lewis, Melissa A Haendel, Helen Parkinson, and Peter N Robinson
MMP21 is mutated in human heterotaxy and is required for normal left-right asymmetry in vertebrates., Anne Guimier, George C Gabriel, Fanny Bajolle, Michael Tsang, Hui Liu, Aaron Noll, Molly Schwartz, Rajae El Malti, Laurie D Smith, Nikolai T Klena, Gina Jimenez, Neil A Miller, Myriam Oufadem, Anne Moreau de Bellaing, Hisato Yagi, Carol J Saunders, Candice N Baker, Sylvie Di Filippo, Kevin A Peterson, Isabelle Thiffault, Christine Bole-Feysot, Linda D Cooley, Emily G Farrow, Cécile Masson, Patric Schoen, Jean-François Deleuze, Patrick Nitschké, Stanislas Lyonnet, Loic de Pontual, Stephen A. Murray, Damien Bonnet, Stephen F Kingsmore, Jeanne Amiel, Patrice Bouvagnet, Cecilia W Lo, and Christopher T Gordon
CbGRiTS: Cerebellar gene regulation in time and space., Thomas Ha, Douglas Swanson, Matt Larouche, Randy Glenn, Dave Weeden, Peter Zhang, Kristin Hamre, Michael Langston, Charles Phillips, Mingzhou Song, Zhengyu Ouyang, Elissa J. Chesler, Suman Duvvurru, Roumyana Yordanova, Yan Cui, Kate Campbell, Greg Ricker, Carey Phillips, Ramin Homayouni, and Dan Goldowitz
Mouse anatomy ontologies: enhancements and tools for exploring and integrating biomedical data., Terry F. Hayamizu, Richard A Baldock, and Martin Ringwald
Genetic Background Effects on Disease Onset and Lifespan of the Mutant Dynactin p150Glued Mouse Model of Motor Neuron Disease., Terry D Heiman-Patterson, Elizabeth P Blankenhorn, Roger B Sher, Juliann Jiang, Priscilla Welsh, Meredith C Dixon, Jeremy I Jeffrey, Philip Wong, Gregory A. Cox, and Guillermo M Alexander
CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase., Weiwei He, Ge Bai, Huihao Zhou, Na Wei, Nicholas M White, Janelle Lauer, Huaqing Liu, Yi Shi, Calin Dan Dumitru, Karen Lettieri, Veronica Shubayev, Albena Jordanova, Velina Guergueltcheva, Patrick R Griffin, Robert W. Burgess, Samuel L Pfaff, and Xiang-Lei Yang
A Patient-Derived Xenograft Model of Parameningeal Embryonal Rhabdomyosarcoma for Preclinical Studies., Jody E Hooper, Emma L Cantor, Macgregor S Ehlen, Avirup Banerjee, Suman Malempati, Peter Stenzel, Randy L Woltjer, Regina Gandour-Edwards, Neal C Goodwin, Yan Yang, Pali Kaur, Carol J Bult, Susan Airhart, and Charles Keller
Sequencing strategies and characterization of 721 vervet monkey genomes for future genetic analyses of medically relevant traits., Yu S Huang, Vasily Ramensky, Susan K Service, Anna J Jasinska, Yoon Jung, Oi-Wa Choi, Rita M Cantor, Nikoleta Juretic, Jessica Wasserscheid, Jay R Kaplan, Matthew J Jorgensen, Thomas D Dyer, Ken Dewar, John Blangero, Richard K Wilson, Wesley Warren, George M. Weinstock, and Nelson B Freimer
DBA/2J genetic background exacerbates spontaneous lethal seizures but lessens amyloid deposition in a mouse model of Alzheimer's disease., Harriet M. Jackson, Kristen D. Onos, Keating W. Pepper, Leah C. Graham, Ellen C. Akeson, Candice Byers, Laura G. Reinholdt, Wayne N. Frankel, and Gareth R. Howell
IL-21-Driven Neoplasms in SJL Mice Mimic Some Key Features of Human Angioimmunoblastic T-Cell Lymphoma., Shweta Jain, Jing Chen, Alina Nicolae, Hongsheng Wang, Dong-Mi Shin, Elisabeth B. Adkins, Thomas J. Sproule, Caroline M Leeth, Tomomi Sakai, Alexander L Kovalchuk, Mark Raffeld, Jerrold M Ward, Jerold E Rehg, Thomas A Waldmann, Elaine S Jaffe, Derry C. Roopenian, and Herbert C Morse
Dengue virus infection induces broadly cross-reactive human IgM antibodies that recognize intact virions in humanized BLT-NSG mice., Smita Jaiswal, Kenneth Smith, Alejandro Ramirez, Marcia Woda, Pamela Pazoles, Leonard D. Shultz, Dale L Greiner, Michael A Brehm, and Anuja Mathew
Corticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 Function., Javier H Jara, Barış Genç, Gregory A. Cox, Martha C Bohn, Raymond P Roos, Jeffrey D Macklis, Emel Ulupınar, and P Hande Özdinler
TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models., Taylor R Jay, Crystal M Miller, Paul J Cheng, Leah C. Graham, Shane Bemiller, Margaret L Broihier, Guixiang Xu, Daniel Margevicius, J Colleen Karlo, Gregory L Sousa, Anne C Cotleur, Oleg Butovsky, Lynn Bekris, Susan M Staugaitis, James B Leverenz, Sanjay W Pimplikar, Gary E Landreth, Gareth R. Howell, Richard M Ransohoff, and Bruce T Lamb
Loss of Clcc1 Results in ER Stress, Misfolded Protein Accumulation, and Neurodegeneration., Yichang Jia, Thomas J. Jucius, Susan A. Cook, and Susan L. Ackerman
A QTL on Chr 5 modifies hearing loss associated with the fascin-2 variant of DBA/2J mice., Kenneth R. Johnson, Chantal M. Longo-Guess, and Leona H. Gagnon
ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype., Simon Junankar, Laura A Baker, Daniel L Roden, Radhika Nair, Ben Elsworth, David Gallego-Ortega, Paul Lacaze, Aurélie Cazet, Iva Nikolic, Wee Siang Teo, Jessica Yang, Andrea McFarland, Kate Harvey, Matthew J Naylor, Sunil R Lakhani, Peter T Simpson, Ashwini Raghavendra, Jodi Saunus, Jason Madore, Warren Kaplan, Christopher Ormandy, Ewan K A Millar, Sandra O'Toole, Kyuson Yun, and Alexander Swarbrick