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Submissions from 2015

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High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9., Gaurav K Varshney, Wuhong Pei, Matthew C LaFave, Jennifer Idol, Lisha Xu, Viviana Gallardo, Blake Carrington, Kevin Bishop, MaryPat Jones, Mingyu Li, Ursula Harper, Sunny C Huang, Anupam Prakash, Wenbiao Chen, Raman Sood, Johan Ledin, and Shawn M Burgess

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Biology and therapy of inherited retinal degenerative disease: insights from mouse models., Shobi Veleri, Csilla H Lazar, Bo Chang, Paul A Sieving, Eyal Banin, and Anand Swaroop

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Vestibular dysfunction, altered macular structure and trait localization in A/J inbred mice., Sarath Vijayakumar, Teresa E Lever, Jessica Pierce, Xing Zhao, David E. Bergstrom, Yunxia Wang Lundberg, Timothy A Jones, and Sherri M Jones

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Affinity-seq detects genome-wide PRDM9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usage., Michael Walker, Timothy Billings, Christopher L. Baker, Natalie Powers, Hui Tian, Ruth L. Saxl, Kwangbom Choi, Matthew A. Hibbs, Gregory W. Carter, Mary Ann Handel, and Petko M. Petkov

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Cloning and variation of ground state intestinal stem cells., Xia Wang, Yusuke Yamamoto, Lane H. Wilson, Ting Zhang, Brooke E Howitt, Melissa A Farrow, Florian Kern, Gang Ning, Yue Hong, Chiea Chuen Khor, Benoit Chevalier, Denis Bertrand, Lingyan Wu, Niranjan Nagarajan, Francisco A Sylvester, Jeffrey S Hyams, Thomas Devers, Roderick Bronson, D Borden Lacy, Khek Yu Ho, Christopher P Crum, Frank D. McKeon, and Wa Xian

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The genome of the vervet (Chlorocebus aethiops sabaeus)., Wesley C Warren, Anna J Jasinska, Raquel García-Pérez, Hannes Svardal, Chad Tomlinson, Mariano Rocchi, Nicoletta Archidiacono, Oronzo Capozzi, Patrick Minx, Michael J Montague, Kim Kyung, LaDeana W Hillier, Milinn Kremitzki, Tina Graves, Colby Chiang, Jennifer Hughes, Nam Tran, Yu Huang, Vasily Ramensky, Oi-Wa Choi, Yoon J Jung, Christopher A Schmitt, Nikoleta Juretic, Jessica Wasserscheid, Trudy R Turner, Roger W Wiseman, Jennifer J Tuscher, Julie A Karl, Jörn E Schmitz, Roland Zahn, David H O'Connor, Eugene Redmond, Alex Nisbett, Béatrice Jacquelin, Michaela C Müller-Trutwin, Jason M Brenchley, Michel Dione, Martin Antonio, Gary P Schroth, Jay R Kaplan, Matthew J Jorgensen, Gregg W C Thomas, Matthew W Hahn, Brian J Raney, Bronwen Aken, Rishi Nag, Juergen Schmitz, Gennady Churakov, Angela Noll, Roscoe Stanyon, David Webb, Francoise Thibaud-Nissen, Magnus Nordborg, Tomas Marques-Bonet, Ken Dewar, George M. Weinstock, Richard K Wilson, and Nelson B Freimer

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Transcriptomic diversification of developing cumulus and mural granulosa cells in mouse ovarian follicles., Karen Wigglesworth, Kyung-Bon Lee, Chihiro Emori, Koji Sugiura, and John J. Eppig

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CRISPR-Cas9-mediated genome editing and guide RNA design., Michael V. Wiles, Wenning Qin, Albert W. Cheng, and Haoyi Wang

Initial locomotor sensitivity to cocaine varies widely among inbred mouse strains., T Wiltshire, R B Ervin, H Duan, Molly A. Bogue, W C Zamboni, S Cook, W Chung, F Zou, and L M Tarantino

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Studies of OC-STAMP in Osteoclast Fusion: A New Knockout Mouse Model, Rescue of Cell Fusion, and Transmembrane Topology., Hanna Witwicka, Sung-Yong Hwang, Pablo Reyes-Gutierrez, Hong Jia, Paul E Odgren, Leah Rae Donahue, Mark J Birnbaum, and Paul R Odgren

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NHE8 Is Essential for RPE Cell Polarity and Photoreceptor Survival., Chun-Hong Xia, Haiquan Liu, Debra Cheung, Felicia Tang, Bo Chang, Mei Li, and Xiaohua Gong

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Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD-scid IL-2rg(null) RIP-DTR mice engrafted with human islets., Chaoxing Yang, Matthias Loehn, Agata Jurczyk, Natalia Przewozniak, Linda Leehy, Pedro L Herrera, Leonard D. Shultz, Dale L Greiner, David M Harlan, and Rita Bortell

Microanatomy of the cervical and anorectal squamocolumnar junctions: a proposed model for anatomical differences in HPV-related cancer risk., Eric J Yang, Matthew C Quick, Suchanan Hanamornroongruang, Keith Lai, Leona A Doyle, Frank D. McKeon, Wa Xian, Christopher P Crum, and Michael Herfs

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Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis., Ning Yang, Li Li, Thibaut Eguether, John P. Sundberg, Gregory J Pazour, and Jiang Chen

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Recurrent Fusion Genes in Gastric Cancer: CLDN18-ARHGAP26 Induces Loss of Epithelial Integrity., Fei Yao, Jaya P Kausalya, Yee Yen Sia, Audrey S M Teo, Wah Heng Lee, Alicia G M Ong, Zhenshui Zhang, Joanna H J Tan, Guoliang Li, Denis Bertrand, Xingliang Liu, Huay Mei Poh, Peiyong Guan, Feng Zhu, Thushangi Nadeera Pathiraja, Pramila N Ariyaratne, Jaideepraj Rao, Xing Yi Woo, Shaojiang Cai, Fabianus H Mulawadi, Wan Ting Poh, Lavanya Veeravalli, Chee Seng Chan, Seong Soo Lim, See Ting Leong, Say Chuan Neo, Poh Sum D Choi, Elaine G Y Chew, Niranjan Nagarajan, Pierre-Étienne Jacques, Jimmy B Y So, Xiaoan Ruan, Khay Guan Yeoh, Patrick Tan, Wing-Kin Sung, Walter Hunziker, Yijun Ruan, and Axel M Hillmer

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The genome sequence of Sea-Island cotton (Gossypium barbadense) provides insights into the allopolyploidization and development of superior spinnable fibres., Daojun Yuan, Zhonghui Tang, Maojun Wang, Wenhui Gao, Lili Tu, Xin Jin, Lingling Chen, Yonghui He, Lin Zhang, Longfu Zhu, Yang Li, Qiqi Liang, Zhongxu Lin, Xiyan Yang, Nian Liu, Shuangxia Jin, Yang Lei, Yuanhao Ding, Guoliang Li, Xiaoan Ruan, Yijun Ruan, and Xianlong Zhang

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Genetic Regulation of Female Sexual Maturation and Longevity Through Circulating IGF1., Rong Yuan, Daniel Mario Gatti, Rebecca Krier, Ethan Malay, David Schultz, Luanne L. Peters, Gary A. Churchill, David E. Harrison, and Beverly Paigen

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Selection of models for the analysis of risk-factor trees: leveraging biological knowledge to mine large sets of risk factors with application to microbiome data., Qunyuan Zhang, Haley Abel, Alan Wells, Petra Lenzini, Felicia Gomez, Michael A Province, Alan A Templeton, George M. Weinstock, Nita H Salzman, and Ingrid B Borecki

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Identification of Candidate Adherent-Invasive E. coli Signature Transcripts by Genomic/Transcriptomic Analysis., Yuanhao Zhang, Leahana Rowehl, Julia M Krumsiek, Erika P Orner, Nurmohammad Shaikh, Phillip I Tarr, Erica Sodergren Weinstock, George M. Weinstock, Edgar C Boedeker, Xuejian Xiong, John Parkinson, Daniel N Frank, Ellen Li, and Grace Gathungu

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Elevation of 20-carbon long chain bases due to a mutation in serine palmitoyltransferase small subunit b results in neurodegeneration., Lihong Zhao, Stefka Spassieva, Kenneth Gable, Sita D Gupta, Lan-Ying Shi, Jieping Wang, Jacek Bielawski, Wanda L. Hicks, Mark P. Krebs, Juergen Naggert, Yusuf A Hannun, Teresa M Dunn, and Patsy M. Nishina

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Longitudinal analysis of the premature infant intestinal microbiome prior to necrotizing enterocolitis: a case-control study., Yanjiao Zhou, Gururaj Shan, Erica Sodergren Weinstock, George M. Weinstock, W Allan Walker, and Katherine E Gregory

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A unified gene catalog for the laboratory mouse reference genome., Y Zhu, Joel E Richardson, Paul Hale, Richard M. Baldarelli, Deborah J. Reed, Jill M. Recla, R Sinclair, T B K Reddy, and Carol J. Bult

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Joint modeling of RNase footprint sequencing profiles for genome-wide inference of RNA structure., Chenchen Zou and Zhengqing Ouyang

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p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration., Wei Zuo, Ting Zhang, Daniel Zheng'An Wu, Shou Ping Guan, Audrey-Ann Liew, Yusuke Yamamoto, Xia Wang, Siew Joo Lim, Matthew Vincent, Mark Lessard, Christopher P Crum, Wa Xian, and Frank D. McKeon