Analysis of morphine responses in mice reveals a QTL on Chromosome 7.
Document Type
Article
Publication Date
9-2-2016
JAX Source
F1000Res 2016 Sep 2; 5:2156
Volume
5
First Page
2156
Last Page
2156
PMID
27746909
Abstract
In this study we identified a quantitative trait locus (QTL) on mouse Chromosome 7 associated with locomotor activity and rearing post morphine treatment. This QTL was revealed after correcting for the effects of another QTL peak on Chromosome 10 using composite interval mapping. The positional candidate genes are Syt9 and Ppfibp2. Several other genes within the interval are linked to neural processes, locomotor activity, and the defensive response to harmful stimuli. F1000Res 2016 Sep 2; 5:2156
Recommended Citation
Crusio W,
Dhawan E,
Chesler E,
Delprato A.
Analysis of morphine responses in mice reveals a QTL on Chromosome 7. F1000Res 2016 Sep 2; 5:2156