Title

Mouse Genome Informatics (MGI) Is the International Resource for Information on the Laboratory Mouse.

Document Type

Article

Publication Date

2018

JAX Location

Reprint Collection

JAX Source

Methods Mol Biol 2018; 1757:141-161

PMID

29761459

DOI

https://doi.org/10.1007/978-1-4939-7737-6_7

Abstract

Mouse Genome Informatics (MGI, http://www.informatics.jax.org/ ) web resources provide free access to meticulously curated information about the laboratory mouse. MGI's primary goal is to help researchers investigate the genetic foundations of human diseases by translating information from mouse phenotypes and disease models studies to human systems. MGI provides comprehensive phenotypes for over 50,000 mutant alleles in mice and provides experimental model descriptions for over 1500 human diseases. Curated data from scientific publications are integrated with those from high-throughput phenotyping and gene expression centers. Data are standardized using defined, hierarchical vocabularies such as the Mammalian Phenotype (MP) Ontology, Mouse Developmental Anatomy and the Gene Ontologies (GO). This chapter introduces you to Gene and Allele Detail pages and provides step-by-step instructions for simple searches and those that take advantage of the breadth of MGI data integration. Methods Mol Biol 2018; 1757:141-161

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