Document Type

Article

Publication Date

1-2021

Publication Title

Stem Cells Transl Med

Keywords

JMG, Animals, COVID-19, Humans, Regenerative Medicine, SARS-CoV-2

JAX Source

Stem Cells Transl Med 2021 Jan; 10(1):5-13

Volume

10

Issue

1

First Page

5

Last Page

13

ISSN

2157-6580

PMID

32856432

DOI

https://doi.org/10.1002/sctm.20-0245

Abstract

This perspective from a Regenerative Medicine Manufacturing Society working group highlights regenerative medicine therapeutic opportunities for fighting COVID-19. This article addresses why SARS-CoV-2 is so different from other viruses and how regenerative medicine is poised to deliver new therapeutic opportunities to battle COVID-19. We describe animal models that depict the mechanism of action for COVID-19 and that may help identify new treatments. Additionally, organoid platforms that can recapitulate some of the physiological properties of human organ systems, such as the lungs and the heart, are discussed as potential platforms that may prove useful in rapidly screening new drugs and identifying at-risk patients. This article critically evaluates some of the promising regenerative medicine-based therapies for treating COVID-19 and presents some of the collective technologies and resources that the scientific community currently has available to confront this pandemic.

Comments

This is an open access article under the terms of the Creative Commons Attribution License.

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