The Th1/Tfh-like biased responses elicited by the rASP-1 innate adjuvant are dependent on TRIF and Type I IFN receptor pathways.

Authors

Parakkal Jovvian George
Radu Marches, The Jackson LaboratoryFollow
Djamel Nehar-Belaid, The Jackson LaboratoryFollow
Jacques Banchereau, The Jackson LaboratoryFollow
Sara Lustigman

Document Type

Article

Publication Date

1-1-2022

Publication Title

Front Immunol

Keywords

JGM, Adaptor Proteins, Vesicular Transport, Adjuvants, Immunologic, Adjuvants, Pharmaceutic, Animals, Chemokine CXCL10, Humans, Influenza A Virus, H1N1 Subtype, Influenza Vaccines, Interleukin-12 Subunit p40, Interleukin-17, Mice, Myeloid Differentiation Factor 88, Receptor, Interferon alpha-beta, Toll-Like Receptor 4, Tumor Necrosis Factor-alpha

JAX Source

Front Immunol. 2022;13:961094.

Volume

13

First Page

961094

ISSN

1664-3224

PMID

36119026

DOI

https://doi.org/10.3389/fimmu.2022.961094

Grant

This research was funded by NIH grants U01AI124260 and U01AI160421.

Comments

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).

Recommended Citation

George P, Marches R, Nehar-Belaid D, Banchereau J, Lustigman S. The Th1/Tfh-like biased responses elicited by the rASP-1 innate adjuvant are dependent on TRIF and Type I IFN receptor pathways. Front Immunol. 2022;13:961094.