Document Type

Article

Publication Date

1-1-2022

Publication Title

Brain plasticity (Amsterdam, Netherlands)

Keywords

JMG, Alzheimer’s Disease, Parkinson’s Disease, blood vessels, cardiorespiratory fitness, cerebrovasculature, cognition, exercise, mitochondria, neurotrophins

JAX Source

Brain Plast . 2022 Dec 20;8(2):153-168.

Volume

8

Issue

2

First Page

153

Last Page

168

PMID

36721393

DOI

10.3233/BPL-220146

Grant

The work was supported by P30AG072973, P30AG035982 (S. Billinger); by NIH R01DK10 9948, Sarns Family Gift to the University of Michi- gan School of Kinesiology (J.M. Haus); by NIH R01DK121995, NIH R01DK107282, and by an American Diabetes Association grant (1–19-IBS- 252) (D.A. Sandoval), and in part, by NIH grants HL-50306, HL-137156, HL-108328, AG 078060 and AG 19228, the Johnson Cancer Research Center (A 21-0645) and a K-State College of Veterinary Medicine Sustained Momentum for Investigators with Laboratories Established (S.M.I.L.E.) Award ´ (D.C. Poole); by the Minist` ere de l’ Education, du Loisir et du Sport du Qu´ ebec and the Fundation of the Institut Universitaire de Cardiologie et Pneumologie de Qu´ ebec (P. Brassard).

Abstract

An inaugural workshop supported by "The Leo and Anne Albert Charitable Trust," was held October 4-7, 2019 in Scottsdale, Arizona, to focus on the effects of exercise on the brain and to discuss how physical activity may prevent or delay the onset of aging-related neurodegenerative conditions. The Scientific Program Committee (led by Dr. Jeff Burns) assembled translational, clinical, and basic scientists who research various aspects of the effects of exercise on the body and brain, with the overall goal of gaining a better understanding as to how to delay or prevent neurodegenerative diseases. In particular, research topics included the links between cardiorespiratory fitness, the cerebrovasculature, energy metabolism, peripheral organs, and cognitive function, which are all highly relevant to understanding the effects of acute and chronic exercise on the brain. The Albert Trust workshop participants addressed these and related topics, as well as how other lifestyle interventions, such as diet, affect age-related cognitive decline associated with Alzheimer's and other neurodegenerative diseases. This report provides a synopsis of the presentations and discussions by the participants, and a delineation of the next steps towards advancing our understanding of the effects of exercise on the aging brain.

Comments

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC 4.0).

Download

Share

COinS